Evidence map›Paper›PMID 34691334›Full record

ArticleJournal of medical cases2021

Delayed Diagnosis of Cardiac Amyloidosis Secondary to Multiple Myeloma.

Ahmad Qatanani, Shereen Dahab, Steven Douedi, Yumna Hamid, Sameh Girgis, Steven Daniels, Gurpreet Lamba, Mohammad Zafar

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of medical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ahmad QatananiDepartment of Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Shereen DahabDepartment of Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Steven DouediDepartment of Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Yumna HamidDepartment of Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Sameh GirgisDepartment of Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Steven DanielsDepartment of Cardiology, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Gurpreet LambaDepartment of Hematology & Oncology, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Mohammad ZafarDepartment of Nephrology, Jersey Shore University Medical Center, Neptune, NJ 07753, USA.
Jersey Shore University Medical Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Cardiac amyloidosis is a rare condition with only 2,500 new cases reported yearly in the United States of America (USA). The prognosis of cardiac amyloidosis is particularly grim. The median survival is 6 months from onset of congestive heart failure (CHF) symptoms. CHF is a common presentation as the second leading cause of hospitalization in the senile population in the USA. We report a case of an 83-year-old man who presented with the classic symptoms of CHF including bilateral lower extremity edema, shortness of breath, and weight gain. Upon further workup, an echocardiogram revealed strain patterns suggestive of cardiac amyloidosis and bone marrow biopsy confirmed the diagnosis of multiple myeloma. Unfortunately, despite starting treatment with steroids and chemotherapy, the patient succumbed to his condition in a matter of weeks. We report this case to highlight that cardiac amyloidosis secondary to multiple myeloma can present in the form of new onset, quickly deteriorating CHF long before any classic multiple myeloma symptoms manifest.

Indexed as

Cardiac amyloidosisCongestive heart failureMultiple myeloma

Identifiers

PMID34691334
PMCPMC8510665
OpenAlexW3202298702

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.