Evidence map›Paper›PMID 34691247›Full record

ArticleOncology letters2021

Membranous CD44v6 is upregulated as an early event in colorectal cancer: Downregulation is associated with circulating tumor cells and poor prognosis.

Agapi Kataki, Vassilis G Giannakoulis, Anastasia Derventzi, Konstantinos Papiris, Eythimios Koniaris, Manousos Konstadoulakis

Abstract read
In one paragraph

Article in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Agapi KatakiFirst Department of Propaedeutic Surgery, Hippokration General Hospital of Athens, Athens 11527, Greece.
Vassilis G GiannakoulisFirst Department of Propaedeutic Surgery, Hippokration General Hospital of Athens, Athens 11527, Greece.
Anastasia DerventziFirst Department of Propaedeutic Surgery, Hippokration General Hospital of Athens, Athens 11527, Greece.
Konstantinos PapirisDepartment of Endoscopy, Hippokration General Hospital of Athens, Athens 11527, Greece.
Eythimios KoniarisDepartment of Pathology, Hippokration General Hospital of Athens, Athens 11527, Greece.
Manousos KonstadoulakisSecond Surgery Clinic, Aretaieio Hospital, Athens Medical School, National and Kapodistrian University of Athens, Athens 11528, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have reported that CD44 variant 6 (CD44v6) and metastasis-associated protein 1 (MTA1) are contributing factors to cancer progression. The present study aimed to evaluate the expression profiles for associations with patients' demographic data, clinicopathological characteristics, the presence of partial epithelial-to-mesenchymal transition (pEMT), metastatic potential based on the presence of CK20

Indexed as

circulating tumor cellscolorectal cancermembranous CD44 variant 6metastasis-associated protein 1polypstumor microenvironment

Identifiers

PMID34691247
PMCPMC8527563

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.