Evidence map›Paper›PMID 34691215›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Desensitization of TRPV1 Involved in the Antipruritic Effect of Osthole on Histamine-Induced Scratching Behavior in Mice.

Niuniu Yang, Ying Ju, Delun Huang, Kunhong Ling, Han Jin, Jiamin Liu, Jing Ma, Yongxin Chen, Yingge Zhang, Chan Zhu and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Niuniu YangDepartment of Traditional Chinese and Western Medicine, College of Medicine, Yangzhou University, Yangzhou 225009, China.ORCID https://orcid.org/0000-0002-3335-3887
Ying JuSchool of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Delun HuangCollege of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530299, China.
Kunhong LingCollege of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530299, China.
Han JinDepartment of Traditional Chinese and Western Medicine, College of Medicine, Yangzhou University, Yangzhou 225009, China.
Jiamin LiuCollege of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530299, China.
Jing MaCollege of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530299, China.
Yongxin ChenCollege of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530299, China.
Yingge ZhangCollege of Pharmacology, Guangxi Medical University, Nanning 530200, China.
Chan ZhuSchool of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Yan YangSchool of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zongxiang TangSchool of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Xi ChenCollege of Pharmacology, Guangxi Medical University, Nanning 530200, China.
Guanyi WuCollege of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530299, China.ORCID https://orcid.org/0000-0002-7294-0902
Guangxi University · CNNanjing University of Chinese Medicine · CNGuangxi Medical University · CNYangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osthole has been isolated from the fruits of

Identifiers

PMID34691215
PMCPMC8528571
OpenAlexW3206010980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.