Evidence map›Paper›PMID 34691069›Full record

ArticleFrontiers in immunology2021

The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (

Abhinandan Chowdhury, Matthew R Lewin, Christina N Zdenek, Rebecca Carter, Bryan G Fry

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Snake Venom PLAToxins · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Toxicon: X · 2022
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Abhinandan ChowdhuryVenom Evolution Lab, School of Biological Science, University of Queensland, St. Lucia, QLD, Australia.
Matthew R LewinCalifornia Academy of Sciences, San Francisco, CA, United States.
Christina N ZdenekVenom Evolution Lab, School of Biological Science, University of Queensland, St. Lucia, QLD, Australia.
Rebecca CarterOphirex, Inc., Corte Madera, CA, United States.
Bryan G FryVenom Evolution Lab, School of Biological Science, University of Queensland, St. Lucia, QLD, Australia.
University of Queensland · AUCalifornia Academy of Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African spitting cobras are unique among cobras for their potent anticoagulant venom activity arising from strong inhibition of Factor Xa. This anticoagulant effect is exerted by venom phospholipase A

Indexed as

AcetatesAfricaAnimalsAntiveninsEnzyme InhibitorsHydroxamic AcidsIndolesIn Vitro TechniquesKeto AcidsNajaOrganic ChemicalsSnake BitesSnake VenomsAcetatesAntiveninsEnzyme InhibitorsHydroxamic AcidsIndolesKeto AcidsmarimastatOrganic ChemicalsprinomastatSnake VenomsvarespladibanticoagulantenzymeFactor Xainhibitorvenom

Identifiers

PMID34691069
PMCPMC8529177
OpenAlexW3204942241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.