Evidence map›Paper›PMID 34691037›Full record

ArticleFrontiers in immunology2021

NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation.

Xiaolong Wu, Amit Sharma, Johannes Oldenburg, Hans Weiher, Markus Essler, Dirk Skowasch, Ingo G H Schmidt-Wolf

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaolong WuDepartment of Integrated Oncology, Center of Integrated Oncology (CIO) Bonn, University Hospital Bonn, Bonn, Germany.
Amit SharmaDepartment of Integrated Oncology, Center of Integrated Oncology (CIO) Bonn, University Hospital Bonn, Bonn, Germany.
Johannes OldenburgInstitute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
Hans WeiherDepartment of Applied Natural Sciences, Bonn-Rhein-Sieg University of Applied Sciences, Rheinbach, Germany.
Markus EsslerDepartment of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Dirk SkowaschDepartment of Internal Medicine II, University Hospital Bonn, Bonn, Germany.
Ingo G H Schmidt-WolfDepartment of Integrated Oncology, Center of Integrated Oncology (CIO) Bonn, University Hospital Bonn, Bonn, Germany.
University Hospital Bonn · DEHochschule Bonn-Rhein-Sieg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytokine-induced killer (CIK) cells are an

Indexed as

Lymphocyte ActivationAnimalsCell DegranulationCoculture TechniquesCytokine-Induced Killer CellsCytotoxicity, ImmunologicHistocompatibility Antigens Class IHumansInterferon-gammaK562 CellsLymphocyte Function-Associated Antigen-1MiceNK Cell Lectin-Like Receptor Subfamily KPhenotypeSignaling Lymphocytic Activation Molecule FamilySignal TransductionCD244 protein, humanHistocompatibility Antigens Class IIFNG protein, humanInterferon-gammaKLRK1 protein, humanLymphocyte Function-Associated Antigen-1MHC class I-related chain AMICB antigenNK Cell Lectin-Like Receptor Subfamily KSignaling Lymphocytic Activation Molecule Family2B4cytokine-induced killer (CIK) cellsLFA-1MICA/BNKG2D

Identifiers

PMID34691037
PMCPMC8529192
OpenAlexW3202422882

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.