Evidence map›Paper›PMID 34691033›Full record

ArticleFrontiers in immunology2021

γδT Cells Are Required for CD8

Rui Dai, Xiaopei Huang, Yiping Yang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rui DaiDepartment of Medicine, Duke University Medical Center, Durham, NC, United States.
Xiaopei HuangDepartment of Medicine, Duke University Medical Center, Durham, NC, United States.
Yiping YangDepartment of Medicine, Duke University Medical Center, Durham, NC, United States.

Funding

Novel Strategies for Cancer Immunotherapy in Stem Cell TransplantR01CA136934 · NCI · OHIO STATE UNIVERSITY · PI YANG, YIPING · 2009 to 2018
$3.4M
Role of macrophage polarization in multi-organ fibrosis of chronic GVHDR01HL151195 · NHLBI · OHIO STATE UNIVERSITY · PI HUANG, XIAOPEI · 2020 to 2023
$2.2M
T Memory Stem Cells in CancerR01CA193167 · NCI · OHIO STATE UNIVERSITY · PI YANG, YIPING · 2016 to 2020
$2.2M
Regulation of tumor-infiltrating T cells by macrophagesR01CA260858 · NCI · OHIO STATE UNIVERSITY · PI HUANG, XIAOPEI · 2021 to 2025
$2.2M
NCI NIH HHS R01 CA136934NCI NIH HHS R01 CA193167NCI NIH HHS R01 CA260858NHLBI NIH HHS R01 HL151195
6 · The paper itself

Abstract

Vaccinia virus (VV) is the most studied member of the poxvirus family, is responsible for the successful elimination of smallpox worldwide, and has been developed as a vaccine vehicle for infectious diseases and cancer immunotherapy. We have previously shown that the unique potency of VV in the activation of CD8

Indexed as

AnimalsAntigen PresentationAntigens, ViralCD8-Positive T-LymphocytesIntraepithelial LymphocytesMiceMice, Inbred C57BLMice, KnockoutVacciniaVaccinia virusAntigens, Viraladaptive immunityCD8 T cellsinnate immunityMyD88 pathwayvaccinia virusγδT cells

Identifiers

PMID34691033
PMCPMC8531544

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.