Evidence map›Paper›PMID 34690988›Full record

ArticleFrontiers in microbiology2021

Combining CRISPR-Cas12a-Based Technology and Metagenomics Next Generation Sequencing: A New Paradigm for Rapid and Full-Scale Detection of Microbes in Infectious Diabetic Foot Samples.

Yixin Chen, Ya Shi, Weifen Zhu, Jiaxing You, Jie Yang, Yaping Xie, Hanxin Zhao, Hongye Li, Shunwu Fan, Lin Li and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07391995 (Evaluation of a New Diagnostic Tool), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07391995 recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of a New Diagnostic Tool (MinION) for Identifying Microorganisms in the Foot Wounds of Patients Living With Diabetic Foot Osteomyelitis (DFOM)

TypeobservationalSponsorCentre Hospitalier Universitaire de NīmesRan2026 to 2026Enrolled43ConditionsDiabetes Mellitus, Diabetes Complications, Diabetic Peripheral Neuropathy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Direct metagenomics investigation of non-surgical hard-to-heal wounds: a review.Annals of clinical microbiology and antimicrobials · 2024
    Review
  4. Article
  5. Article
  6. Vancomycin Resistance inMicroorganisms · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yixin ChenDepartment of Endocrinology, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Ya ShiHangzhou Digital Micro Biotech Co., Ltd., Hangzhou, China.
Weifen ZhuDepartment of Endocrinology, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Jiaxing YouDepartment of Orthopedics, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Jie YangDepartment of Orthopedics, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Yaping XieDepartment of Hematology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hanxin ZhaoDepartment of Endocrinology, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Hongye LiDepartment of Orthopedics, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Shunwu FanDepartment of Orthopedics, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Lin LiDepartment of Endocrinology, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Chao LiuDepartment of Orthopedics, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.
Zhejiang University · CNSir Run Run Shaw Hospital · CNHangzhou DAC Biotech (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clustered regularly interspaced short palindromic repeatsdiabetic foot infectionsloop-mediated isothermal amplificationmetagenomics next generation sequencingStaphylococcus aureus

Identifiers

PMID34690988
PMCPMC8529936
OpenAlexW3202497554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.