Evidence map›Paper›PMID 34690770›Full record

ArticleFrontiers in pharmacology2021

Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies.

Darren Shu Jeng Ting, Jianguo Li, Chandra S Verma, Eunice T L Goh, Mario Nubile, Leonardo Mastropasqua, Dalia G Said, Roger W Beuerman, Rajamani Lakshminarayanan, Imran Mohammed and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Darren Shu Jeng TingAcademic Ophthalmology, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Jianguo LiAnti-Infectives Research Group, Singapore Eye Research Institute, Singapore, Singapore.
Chandra S VermaBioinformatics Institute (AStar), Singapore, Singapore.
Eunice T L GohAnti-Infectives Research Group, Singapore Eye Research Institute, Singapore, Singapore.
Mario NubileOphthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Chieti, Italy.
Leonardo MastropasquaOphthalmic Clinic, University "G d'Annunzio" of Chieti-Pescara, Chieti, Italy.
Dalia G SaidAcademic Ophthalmology, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Roger W BeuermanAnti-Infectives Research Group, Singapore Eye Research Institute, Singapore, Singapore.
Rajamani LakshminarayananAnti-Infectives Research Group, Singapore Eye Research Institute, Singapore, Singapore.
Imran MohammedAcademic Ophthalmology, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Harminder S DuaAcademic Ophthalmology, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
University of Nottingham · GBSingapore Eye Research Institute · SGBioinformatics Institute · SGUniversity of Chieti-Pescara · IT

Funding

Medical Research Council MR/T001674/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antibioticantimicrobial peptide (AMP)cathelicidin (LL37)computational simulationdefensindrug designhost defense (antimicrobial) peptidesmolecular dynamics simulations

Identifiers

PMID34690770
PMCPMC8528955
OpenAlexW3175514168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.