Evidence map›Paper›PMID 34690755›Full record

ArticleFrontiers in pharmacology2021

Gallic Acid Suppressed Tumorigenesis by an LncRNA MALAT1-Wnt/β-Catenin Axis in Hepatocellular Carcinoma.

Chuan-Jian Shi, Yan-Biao Zheng, Fei-Fei Pan, Feng-Wei Zhang, Peng Zhuang, Wei-Ming Fu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  10. LncRNAs in oncogenic microenvironment: from threat to therapy.Frontiers in cell and developmental biology · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Polyphenols as Potent Epigenetics Agents for Cancer.International journal of molecular sciences · 2022
    Review
  18. Potential ofMolecules (Basel, Switzerland) · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chuan-Jian ShiSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Yan-Biao ZhengDepartment of Oncology, The Sixth People's Hospital of Huizhou, Huiyang Hospital Affiliated to Southern Medical University, Huizhou, China.
Fei-Fei PanSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Feng-Wei ZhangKey Laboratory of Orthopaedics and Traumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Peng ZhuangThe Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Wei-Ming FuSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Southern Medical University · CNGuangzhou University of Chinese Medicine · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gallic acid (3,4,5-trihydroxybenzoic acid; GA), a natural phenolic acid, is abundantly found in numerous natural products. Increasing evidence have demonstrated that GA plays anti-cancer roles in multiple cancers. However, its anti-tumor effects on hepatocellular carcinoma (HCC) and the underlying mechanism remain obscure. In the present study, we found that GA suppressed the

Indexed as

gallic acidhepatocellular carcinomalncRNA MALAT1metastasisproliferationWnt/β-catenin signaling

Identifiers

PMID34690755
PMCPMC8526893
OpenAlexW3201685527

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.