Evidence map›Paper›PMID 34690748›Full record

ArticleFrontiers in pharmacology2021

Clinical Attributes and Electroencephalogram Analysis of Patients With Varying Alpers' Syndrome Genotypes.

Hua Li, Wei Wang, Xiaodi Han, Yujia Zhang, Lifang Dai, Manting Xu, Jie Deng, Changhong Ding, Xiaohui Wang, Chunhong Chen and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Clinical and genetic characterization ofFrontiers in pediatrics · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hua LiDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Wei WangLaboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China.
Xiaodi HanDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Yujia ZhangDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Lifang DaiDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Manting XuDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Jie DengDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Changhong DingDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Xiaohui WangDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Chunhong ChenDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Xiaofeng YangBioland Laboratory Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China.
Fang FangDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.
Beijing Children’s Hospital · CNCapital Medical University · CNGuangzhou Regenerative Medicine and Health Guangdong Laboratory · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpers' syndrome is an early inceptive neurodegenerative disorder with a poor prognosis, characterized by developmental regression, intractable epilepsy, and hepatic dysfunction. Candidate genes, such as

Indexed as

AlpersdiagnosiselectroencephalogramPOLGRHADSsyndrome

Identifiers

PMID34690748
PMCPMC8526534
OpenAlexW3201940711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.