ArticleJournal of Alzheimer's disease : JAD2021
Medical and Social Determinants of Brain Health and Dementia in a Multicultural Community Cohort of Older Adults.
Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Cognitive impairment in heart transplantation: prevalence, trajectories, and prognostic impact - a systematic review.Aging clinical and experimental research · 2026Pooled it
- Assessing Functional Cognition in People on Maintenance Hemodialysis Using Performance-Based Testing.Kidney360 · 2026Article
- Associations Between Cardiovascular Risk Factors and Neurofilament Light Levels Among US Mexican American Adults.Brain and behavior · 2026Article
- Resilience and social support as correlates of dementia risk: insights from a biopsychosocial analysis of the All of Us dataset.Frontiers in public health · 2026Article
- Psychometric Reliability, Validity, and Generalizability of MoCA in American Indian Adults: The Strong Heart Study.Assessment · 2025Article
- Biological imprint of education and rights-based brain capital.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Social determinants of health and risk of dementia among older men and women: A 12-year cohort study in Australia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Socioeconomic and medical determinants of state-level subjective cognitive decline in the United States.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Article
- Psychometric reliability, validity, and generalizability of 3MSE scores among American Indian adults: the Strong Heart Study.Journal of the International Neuropsychological Society : JINS · 2024Article
- Data-driven classification of cognitively normal and mild cognitive impairment subtypes predicts progression in the NACC dataset.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Assessing Alzheimer's Disease Knowledge and Cognitive Risk Among a Rural Older Afro-Caribbean Cohort.Journal of community health nursing · 2024Article
- A Targeted Mass Spectrometry Approach to Identify Peripheral Changes in Metabolic Pathways of Patients with Alzheimer's Disease.International journal of molecular sciences · 2023Article
- Diversity of Studies on Neighborhood Greenspace and Brain Health by Racialized/Ethnic Group and Geographic Region: A Rapid Review.International journal of environmental research and public health · 2023Review
- Exploring Reasons for Differential Vulnerability and Alzheimer's Disease Risk in Racial and Ethnic Minorities.Journal of Alzheimer's disease : JAD · 2023Article
- The Brain Health Platform: Combining Resilience, Vulnerability, and Performance to Assess Brain Health and Risk of Alzheimer's Disease and Related Disorders.Journal of Alzheimer's disease : JAD · 2022Article
- Barriers and solutions to Alzheimer's disease clinical trial participation for Black Americans.Alzheimer's & dementia (New York, N. Y.)Review
- The Dementia Literacy Assessment (DeLA): A novel measure of Alzheimer's disease and related disorders health literacy in diverse populations.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSocioeconomic status (SES), race, ethnicity, and medical comorbidities may contribute to Alzheimer's disease and related disorders (ADRD) health disparities.
objectiveAnalyze effects of social and medical determinants on cognition in 374 multicultural older adults participating in a community-based dementia screening program.
methodsWe used the Montreal Cognitive Assessment (MoCA) and AD8 as measures of cognition, and a 3-way race/ethnicity variable (White, African American, Hispanic) and SES (Hollingshead index) as predictors. Potential contributors to health disparities included: age, sex, education, total medical comorbidities, health self-ratings, and depression. We applied K-means cluster analyses to study medical and social dimension effects on cognitive outcomes.
resultsAfrican Americans and Hispanics had lower SES status and cognitive performance compared with similarly aged Whites. We defined three clusters based on age and SES. Cluster #1 and #3 differed by SES but not age, while cluster #2 was younger with midlevel SES. Cluster #1 experienced the worse health outcomes while cluster #3 had the best health outcomes. Within each cluster, White participants had higher SES and better health outcomes, African Americans had the worst physical performance, and Hispanics had the most depressive symptoms. In cross-cluster comparisons, higher SES led to better health outcomes for all participants.
conclusionSES may contribute to disparities in access to healthcare services, while race and ethnicity may contribute to disparities in the quality and extent of services received. Our study highlights the need to critically address potential interactions between race, ethnicity, and SES which may better explain disparities in ADRD health outcomes.
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Registered trials
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