ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2021
Relationship between Handgrip Strength and Low-grade Inflammation in Older Adults with Depression.
Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 8 citations in OpenAlex.
- Article
- Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk.SSM - population health · 2026Article
- The role of depression in the association between handgrip strength and mild cognitive impairment among Chinese older adults.BMC geriatrics · 2026Article
- Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk.medRxiv : the preprint server for health sciences · 2026Article
- Prevalence of depressive symptoms and their association with handgrip strength among middle-aged and older adults in Egypt: a cross-sectional study.Discover public health · 2026Article
- Nonregular Physical Activity and Handgrip Strength as Indicators of Fatigue and Psychological Distress in Cancer Survivors.Current oncology (Toronto, Ont.) · 2025Article
- Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Association between Geriatric Nutrition Risk Index and depression in older hemodialysis patients with and without type 2 diabetes mellitus: a multicenter cross-sectional study.Frontiers in endocrinology · 2025Article
- Association between handgrip strength and depressive symptoms in patients undergoing hemodialysis: a cross-sectional study from a single Chinese center.BMC psychiatry · 2024Article
- Low hand grip strength as an indicator of depression in the Korean population: a large-scale cross-sectional study.Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe relationship among physical functional decline, low-grade inflammation, and depression remains unclear. The aim of this study was to examine the association between hand grip strength (HGS) and high-sensitivity C-reactive protein (hs-CRP) in a large sample with depression.
methodsThis study used data obtained from a representative Korean sample of 9,402 people who participated in the seventh Korean National Health and Nutrition Examination Survey. Physical function was assessed using a digital grip strength dynamometer. Depression was identified using a cutoff of 5 on the Patient Health Questionnaire-9 (PHQ-9), and high hs-CPR level was defined as ≥ 3.0 mg/L.
resultsIn older adults (≥ 60 years) with depression, 43.8% of those with high hs-CRP levels had low HGS, compared to 21.8% of those with hs-CRP levels < 3.0 mg/L (
conclusionThese findings suggest a significant correlation between physical functional decline and low-grade inflammation in older adults with depression.
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