Evidence map›Paper›PMID 34690126›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2021

Effects of Iron Supplementation on Attention Deficit Hyperactivity Disorder in Children Treated with Methylphenidate.

Sepehr Tohidi, Elham Bidabadi, Mohammad-Javad Khosousi, Melika Amoukhteh, Maryam Kousha, Parham Mashouf, Tamkin Shahraki

Open access · diamondAbstract read
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sepehr TohidiStudent Research Committee, School of Medicine, Guilan Universtiy of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0002-9987-5020
Elham BidabadiPediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0002-1067-3335
Mohammad-Javad KhosousiGastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0002-2896-8094
Melika AmoukhtehPediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0003-3488-8960
Maryam KoushaDepartment of Psychiatry, Shafa Hospital, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0002-8101-8258
Parham MashoufEmergency Department, Arya Hospital, Rasht, Iran.ORCID https://orcid.org/0000-0002-0474-4600
Tamkin ShahrakiPediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.ORCID https://orcid.org/0000-0001-6811-8951
Guilan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of iron on the attention deficit hyperactivity disorder, treated with methylphenidate.

methodsThis double-blind, randomized placebo-controlled clinical trial was performed on 50 children with attention deficit hyperactivity disorder under the treatment of methylphenidate, with ferritin levels below 30 ng/ml and absence of anemia. They were randomly assigned into two groups of ferrous sulfate and placebo, for 12 weeks. Conners' Parent Rating Scale (CPRS) was used to assess the outcome in the first, sixth, and twelfth weeks.

resultsAlmost all CPRS subscales improved in the ferrous sulfate group from the baseline to the endpoint, although only the changes in conduct subscale scores were significant (

conclusionOur study showed promising effects of iron supplementation in the improvement of subscales of the CPRS.

Indexed as

Attention deficit disorder with hyperactivityChildIronMethylphenidate

Identifiers

PMID34690126
PMCPMC8553525
OpenAlexW3210390582

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.