Evidence map›Paper›PMID 34689822›Full record

ReviewVirology journal2021

Small but mighty: old and new parvoviruses of veterinary significance.

Mason C Jager, Joy E Tomlinson, Robert A Lopez-Astacio, Colin R Parrish, Gerlinde R Van de Walle

Open access · goldAbstract readReview
In one paragraph

Review in Virology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
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  10. The amazing AAV capsids: Into the structure-verse.Molecular therapy. Methods & clinical development · 2025
    Review
  11. Article
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  20. Genome sequence ofMicrobiology resource announcements · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mason C JagerBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Joy E TomlinsonBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Robert A Lopez-AstacioBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Colin R ParrishBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Gerlinde R Van de WalleBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA. grv23@cornell.edu.ORCID 0000-0002-2064-8029
Cornell University · US

Funding

Graduate Training Program in Comparative MedicineT32OD011000 · OD · CORNELL UNIVERSITY · PI Amanda Marjorie DE MESTRE · 2012 to 2026
$5.7M
Structural Controls of Functional Receptor and Antibody Binding to Viral Capsids.R01AI092571 · NIAID · CORNELL UNIVERSITY · PI PARRISH, COLIN R. · 2011 to 2021
$4.0M
Comparative Animal Models of Viral HepatitisK08AI141767 · NIAID · CORNELL UNIVERSITY · PI TOMLINSON, JOY E · 2019 to 2023
$699k
NIAID NIH HHS K08 AI141767NIAID NIH HHS R01 AI092571NIH HHS T32 OD011000
6 · The paper itself

Abstract

In line with the Latin expression "sed parva forti" meaning "small but mighty," the family Parvoviridae contains many of the smallest known viruses, some of which result in fatal or debilitating infections. In recent years, advances in metagenomic viral discovery techniques have dramatically increased the identification of novel parvoviruses in both diseased and healthy individuals. While some of these discoveries have solved etiologic mysteries of well-described diseases in animals, many of the newly discovered parvoviruses appear to cause mild or no disease, or disease associations remain to be established. With the increased use of animal parvoviruses as vectors for gene therapy and oncolytic treatments in humans, it becomes all the more important to understand the diversity, pathogenic potential, and evolution of this diverse family of viruses. In this review, we discuss parvoviruses infecting vertebrate animals, with a special focus on pathogens of veterinary significance and viruses discovered within the last four years.

Indexed as

ParvoviridaeParvoviridae InfectionsParvovirusAnimalsMetagenomicsPhylogenyAmdoparvovirusAnimal parvovirusesChaphamaparvovirusCopiparvovirusPathogenicityViral metagenomicsViral therapeutics

Identifiers

PMID34689822
PMCPMC8542416
OpenAlexW3208614627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.