Evidence map›Paper›PMID 34689765›Full record

ReviewJournal of nanobiotechnology2021

Recent advances in selective photothermal therapy of tumor.

Liping Zhao, Xu Zhang, Xiaoxia Wang, Xiuwen Guan, Weifeng Zhang, Jinlong Ma

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 2 pooled it
24.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 2 syntheses or guidelines pooled it, 416 citations in OpenAlex.

  1. Pooled it
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81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Liping Zhao *College of Pharmacy, Weifang Medical University, Weifang, 261053, China.
Xu Zhang *School of Clinical Medicine, Weifang Medical University, Weifang, 261053, Shandong, China.
Xiaoxia WangCollege of Pharmacy, Weifang Medical University, Weifang, 261053, China.
Xiuwen GuanCollege of Pharmacy, Weifang Medical University, Weifang, 261053, China.
Weifeng ZhangCollege of Pharmacy, Weifang Medical University, Weifang, 261053, China. zhangwf@wfmc.edu.cn.
Jinlong MaCollege of Pharmacy, Weifang Medical University, Weifang, 261053, China. majinlong99@hotmail.com.ORCID http://orcid.org/0000-0002-4321-9024
Weifang Medical University · CN

Funding

major innovation and technology engineering project of Shandong Province 2019JZZY011106National Natural Science Foundation of China 81774125National Natural Science Foundation of China 81973671Natural Science Foundation of Shandong Province ZR2019BB071
6 · The paper itself

Abstract

Photothermal therapy (PTT), which converts light energy to heat energy, has become a new research hotspot in cancer treatment. Although researchers have investigated various ways to improve the efficiency of tumor heat ablation to treat cancer, PTT may cause severe damage to normal tissue due to the systemic distribution of photothermal agents (PTAs) in the body and inaccurate laser exposure during treatment. To further improve the survival rate of cancer patients and reduce possible side effects on other parts of the body, it is still necessary to explore PTAs with high selectivity and precise treatment. In this review, we summarized strategies to improve the treatment selectivity of PTT, such as increasing the accumulation of PTAs at tumor sites and endowing PTAs with a self-regulating photothermal conversion function. The views and challenges of selective PTT were discussed, especially the prospects and challenges of their clinical applications.

Indexed as

Photothermal TherapyAnimalsHumansMiceNeoplasmsPhotothermal therapySelective killingSelf-regulatingTargeted enrichment

Identifiers

PMID34689765
PMCPMC8543909
OpenAlexW3210065931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.