Evidence map›Paper›PMID 34689760›Full record

ArticleBMC infectious diseases2021

Utility of conventional clinical risk scores in a low-risk COVID-19 cohort.

Jinghao Nicholas Ngiam, Nicholas W S Chew, Sai Meng Tham, Zhen Yu Lim, Tony Y W Li, Shuyun Cen, Paul Anantharajah Tambyah, Amelia Santosa, Ching-Hui Sia, Gail Brenda Cross

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jinghao Nicholas Ngiam *Department of Medicine, National University Health System, Singapore, Singapore.
Nicholas W S Chew *Department of Cardiology, National University Heart Centre Singapore, Singapore, Singapore.
Sai Meng ThamDepartment of Infectious Diseases, National University Health System, 1E Kent Ridge Rd, NUHS Tower Block, Level 10, Singapore, 119228, Singapore.
Zhen Yu LimDepartment of Medicine, National University Health System, Singapore, Singapore.
Tony Y W LiDepartment of Medicine, National University Health System, Singapore, Singapore.
Shuyun CenDepartment of Medicine, National University Health System, Singapore, Singapore.
Paul Anantharajah TambyahDepartment of Infectious Diseases, National University Health System, 1E Kent Ridge Rd, NUHS Tower Block, Level 10, Singapore, 119228, Singapore.
Amelia SantosaDepartment of Rheumatology, National University Health System, Singapore, Singapore.
Ching-Hui SiaDepartment of Cardiology, National University Heart Centre Singapore, Singapore, Singapore.
Gail Brenda CrossDepartment of Infectious Diseases, National University Health System, 1E Kent Ridge Rd, NUHS Tower Block, Level 10, Singapore, 119228, Singapore. mdcgbc@nus.edu.sg.
National University Health System · SGNational University Heart Centre Singapore · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral specific risk scores for Coronavirus disease 2019 (COVID-19) involving clinical and biochemical parameters have been developed from higher-risk patients, in addition to validating well-established pneumonia risk scores. We compared multiple risk scores in predicting more severe disease in a cohort of young patients with few comorbid illnesses. Accurately predicting the progression of COVID-19 may guide triage and therapy.

methodsWe retrospectively examined 554 hospitalised COVID-19 patients in Singapore. The CURB-65 score, Pneumonia Severity Index (PSI), ISARIC 4C prognostic score (4C), CHA

resultsA majority of patients were young (≤ 40 years, n = 372, 67.1%). 57 (10.3%) developed pneumonia, with 16 (2.9% of study population) requiring supplemental oxygen. 19 patients (3.4%) required intensive care and 2 patients (0.5%) died. The clinical risk scores predicted patients who required supplemental oxygenation and intensive care well. Adding the presence of fever to the CHA

conclusionSimple scores including well established pneumonia risk scores can help predict progression of COVID-19. Adding the presence of fever as a parameter to the CHA

Indexed as

COVID-19Hospital MortalityHumansRetrospective StudiesRisk AssessmentRisk FactorsSARS-CoV-2Severity of Illness IndexCOVID-19FeverOutcomesRisk scoreSingapore

Identifiers

PMID34689760
PMCPMC8542362
OpenAlexW3210522553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.