Evidence map›Paper›PMID 34689365›Full record

ArticleJournal of clinical laboratory analysis2021

Underutilization of diagnostic assays for celiac disease in Korea.

Rihwa Choi, Sang Gon Lee, Eun Hee Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Case Series: Is Celiac Disease Underdiagnosed in Korean Children?The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Article
  2. Review
  3. Review
  4. Non-celiac Gluten Sensitivity or Celiac Disease, This Is Still the Question.Journal of neurogastroenterology and motility · 2022
    Article
  5. Underutilization of diagnostic assays for celiac disease in Korea.Journal of clinical laboratory analysis · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Rihwa ChoiDepartment of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8266-2248
Sang Gon LeeDepartment of Laboratory Medicine, Green Cross Laboratories, Yongin, Korea.ORCID https://orcid.org/0000-0002-4672-5811
Eun Hee LeeGreen Cross Laboratories, Yongin, Korea.ORCID https://orcid.org/0000-0002-2517-175X
Green Cross (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTest utilization for the diagnosis of celiac disease may affect the prevalence and incidence of the disease in Korea. We aimed to investigate the test utilization of serological biomarkers for celiac disease in Korea.

methodsWe retrospectively investigated the test utilization of tissue transglutaminase IgA, gliadin IgA and IgG, and endomysial IgA antibody (Ab) assays between January 2011 and June 2020.

resultsDuring a nine-year-and-six-month study period, overall 307,322,606 clinical tests were requested from different clinical settings, such as local clinics, hospitals, university hospitals, and tertiary medical centers. Among them, only 58 tissue transglutaminase IgA, 22 gliadin IgA, 12 gliadin IgG, and 16 endomysial IgA Ab tests were performed on 79 Korean patients. Among them, one patient had positive transglutaminase IgA Ab result (1.3%).

conclusionLow prevalence and incidence of celiac disease in Korea may be due to an underutilization of diagnostic assays.

Indexed as

Celiac DiseaseDiagnostic Tests, RoutineGliadinHumansImmunoglobulin AImmunoglobulin GProtein Glutamine gamma Glutamyltransferase 2Republic of KoreaRetrospective StudiesSerologic TestsGliadinImmunoglobulin AImmunoglobulin GProtein Glutamine gamma Glutamyltransferase 2celiac diseaseendomysial antibodygliadin antibodytest utilizationtransglutaminase antibody

Identifiers

PMID34689365
PMCPMC8649377
OpenAlexW3210604602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.