Evidence map›Paper›PMID 34689290›Full record

ReviewBiochemical genetics2022

The Role of Long Non-coding RNA, Nuclear Enriched Abundant Transcript 1 (NEAT1) in Cancer and Other Pathologies.

Miao Zhang, Jianmin Guo, Lifei Liu, Mei Huang, Yuexuan Li, Samuel Bennett, JiaKe Xu, Jun Zou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biochemical genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Emerging roles of the long non-coding RNA NEAT1 in gynecologic cancers.Journal of cell communication and signaling · 2023
    Review
  10. Functional Roles of lncRNAs in Recurrent Pregnancy Loss: A Review Study.International journal of fertility & sterility · 2023
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Miao ZhangSchool of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China.
Jianmin GuoSchool of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China.
Lifei LiuSchool of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China.
Mei HuangSchool of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China.
Yuexuan LiSchool of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China.
Samuel BennettSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
JiaKe XuSchool of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.
Jun ZouSchool of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China. junzou@sus.edu.cn.ORCID http://orcid.org/0000-0001-6036-8067
Shanghai University of Sport · CNThe University of Western Australia · AU

Funding

National Natural Science Foundation of China 81871835Shanghai Key Laboratory of Human Movement Development and Protection 11DZ2261100
6 · The paper itself

Abstract

Nuclear enriched abundant transcript 1 (NEAT1), consisting of two kinds of lncRNAs of 3.7 kB NEAT1-1 and 23 kB NEAT1-2, can be highly expressed in organs and tissues such as the ovary, prostate, colon, and pancreas, and is involved in paraspeckle formation and mRNA editing and gene expression. Therefore, NEAT1 is a potential biomarker for the treatment of a variety of diseases, which may be caused by two factors (isoforms of NEAT1 and NEAT1 sponging miRNA as ceRNA). However, there is still much confusion about the mechanism and downstream effector between the abnormal expression of NEAT1 and various diseases. This review summarizes recent research progress on NEAT1 in cancer and other pathologies and provides a more reliable theoretical basis for the treatment of related diseases.

Indexed as

MicroRNAsNeoplasmsRNA, Long NoncodingFemaleHumansMaleMicroRNAsNEAT1 long non-coding RNA, humanRNA, Long NoncodingCancerlncRNAsNEAT1Noncancerous

Identifiers

PMID34689290
OpenAlexW3209103545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.