Evidence map›Paper›PMID 34689190›Full record

ArticleThe Journal of nutrition2021

Exploration of Machine Learning and Statistical Techniques in Development of a Low-Cost Screening Method Featuring the Global Diet Quality Score for Detecting Prediabetes in Rural India.

Nick Birk, Mika Matsuzaki, Teresa T Fung, Yanping Li, Carolina Batis, Meir J Stampfer, Megan Deitchler, Walter C Willett, Wafaie W Fawzi, Sabri Bromage and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Nick BirkDepartment of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
Mika MatsuzakiDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-7020-3757
Teresa T FungNutrition Department, Simmons University, Boston, MA, USA.ORCID 0000-0002-0159-482X
Yanping LiDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-0412-2748
Carolina BatisCONACYT-Health and Nutrition Research Center, National Institute of Public Health, Cuernavaca, Mexico.
Meir J StampferDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Megan DeitchlerIntake-Center for Dietary Assessment, FHI Solutions, Washington, DC, USA.
Walter C WillettDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.ORCID 0000-0003-1458-7597
Wafaie W FawziDepartment of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-2908-600X
Sabri BromageDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Sanjay KinraDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, University of London, London, United Kingdom.
Shilpa N BhupathirajuDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
Erin LakeDepartment of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
Harvard University · USBrigham and Women's Hospital · USUniversity of London · GBFamily Health International 360 · USHarvard Global Health Institute · USNational Institute of Public Health · SISimmons University · US

Funding

Wellcome Trust 083707Wellcome Trust 084754
6 · The paper itself

Abstract

backgroundThe prevalence of type 2 diabetes has increased substantially in India over the past 3 decades. Undiagnosed diabetes presents a public health challenge, especially in rural areas, where access to laboratory testing for diagnosis may not be readily available.

objectivesThe present work explores the use of several machine learning and statistical methods in the development of a predictive tool to screen for prediabetes using survey data from an FFQ to compute the Global Diet Quality Score (GDQS).

methodsThe outcome variable prediabetes status (yes/no) used throughout this study was determined based upon a fasting blood glucose measurement ≥100 mg/dL. The algorithms utilized included the generalized linear model (GLM), random forest, least absolute shrinkage and selection operator (LASSO), elastic net (EN), and generalized linear mixed model (GLMM) with family unit as a (cluster) random (intercept) effect to account for intrafamily correlation. Model performance was assessed on held-out test data, and comparisons made with respect to area under the receiver operating characteristic curve (AUC), sensitivity, and specificity.

resultsThe GLMM, GLM, LASSO, and random forest modeling techniques each performed quite well (AUCs >0.70) and included the GDQS food groups and age, among other predictors. The fully adjusted GLMM, which included a random intercept for family unit, achieved slightly superior results (AUC of 0.72) in classifying the prediabetes outcome in these cluster-correlated data.

conclusionsThe models presented in the current work show promise in identifying individuals at risk of developing diabetes, although further studies are necessary to assess other potentially impactful predictors, as well as the consistency and generalizability of model performance. In addition, future studies to examine the utility of the GDQS in screening for other noncommunicable diseases are recommended.

Indexed as

DietDiet, HealthyMachine LearningModels, StatisticalAdolescentAdultAgedAged, 80 and overAlgorithmsBlood GlucoseCross-Sectional StudiesDiabetes Mellitus, Type 2FastingFemaleHumansIndiaBlood Glucosecluster-correlationdiabetesGDQSGLMMLASSOmachine learningmixed modelprediabetesrandom forestsurvey

Identifiers

PMID34689190
PMCPMC8542097
OpenAlexW3211294205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.