Evidence map›Paper›PMID 34689175›Full record

ArticleCell death & disease2021

METTL3-mediated mRNA N

Haiyuan Mu, Ting Zhang, Ying Yang, Danru Zhang, Jie Gao, Junhong Li, Liang Yue, Dengfeng Gao, Bingbo Shi, Yue Han and 8 more

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 81 citations in OpenAlex.

  1. GnRH Promotes Gonadotropin Synthesis and Secretion in the Bovine Anterior Pituitary by Inhibiting METTL1-Mediated m7G Modification of FOXO1 mRNA.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  3. Single-molecule mbioRxiv : the preprint server for biology · 2026
    Article
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  8. mThe EMBO journal · 2026
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  12. The role of mGenes & diseases · 2026
    Review
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Haiyuan Mu *State Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Ting Zhang *Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.
Ying Yang *Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.
Danru Zhang *State Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Jie GaoState Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Junhong LiState Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Liang YueState Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Dengfeng GaoState Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Bingbo ShiState Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Yue HanKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.
Liang ZhongHebei Provincial Key Laboratory of Basic Medicine for Diabetes, The Shijiazhuang Second Hospital, Shijiazhuang, Hebei, 050051, China.
Xinze ChenState Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Zhen-Bo WangUniversity of Chinese Academy of Sciences, Beijing, 100049, China.ORCID 0000-0001-5013-251X
Zhen LinState Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Ming-Han TongState Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Qing-Yuan SunFertility Preservation Lab, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, 510317, China.ORCID 0000-0002-0148-2414
Yun-Gui YangKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China. ygyang@big.ac.cn.ORCID 0000-0002-2821-8541
Jianyong HanState Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China. hanjy@cau.edu.cn.ORCID 0000-0002-9549-3279
China Agricultural University · CNChinese Academy of Sciences · CNCenter for Excellence in Molecular Cell Science · CNGuangdong Provincial People's Hospital · CNHebei Medical University · CN

Funding

Beijing Municipal Science and Technology Commission Z201100006820104CAS | Beijing Institute of Genomics, Chinese Academy of Sciences (Beijing Institute of Genomics) CAS2018133CAU | State Key Laboratory of Agrobiotechnology, China Agricultural University 10052521-01CAU | State Key Laboratory of Agrobiotechnology, China Agricultural University 2020SKLAB1-3Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2016YFA0100202Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2017SHZDZX01Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2019YFA0110901National Natural Science Foundation of China (National Science Foundation of China) 31051378National Natural Science Foundation of China (National Science Foundation of China) 31601941National Natural Science Foundation of China (National Science Foundation of China) 31772601
6 · The paper itself

Abstract

Proper follicle development is very important for the production of mature oocytes, which is essential for the maintenance of female fertility. This complex biological process requires precise gene regulation. The most abundant modification of mRNA, N

Indexed as

AdenosineAnimalsFemaleMethyltransferasesMiceOocytesOvarian FollicleAdenosineMethyltransferasesMettl3 protein, mouseN-methyladenosine

Identifiers

PMID34689175
PMCPMC8542036
OpenAlexW3208328539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.