Evidence map›Paper›PMID 34688949›Full record

ReviewInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Measuring the impact of a single dose of ChAdOx1 nCoV-19 (recombinant) coronavirus vaccine on hospital stay, ICU requirement, and mortality outcome in a tertiary care centre.

Anuja Desai, Parth Desai, Jigar Mehta, Wasimahmed Sachora, Neeraj Bharti, Tushar Patel, Kalpesh Sukhwani, Ankita Jain, Dipesh Sorathiya, Vivek Nanda and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Anuja DesaiDepartment of Ophthalmology, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: dranuja@kdhospital.co.in.
Parth DesaiKusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: parth@kdhospital.co.in.
Jigar MehtaDepartment of Critical Care Medicine, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: drjigar74@yahoo.com.
Wasimahmed SachoraDepartment of General Medicine, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: wasimsachora@yahoo.com.
Neeraj BhartiDepartment of General Medicine, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: neerajbharti2001@gmail.com.
Tushar PatelDepartment of Pulmonary Medicine, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: drtusharpatel@yahoo.com.
Kalpesh SukhwaniDepartment of Infectious Disease, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: kalpesh.sukhwani@gmail.com.
Ankita JainDepartment of Obstetrics and Gynecology, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: drankitajain@yahoo.com.
Dipesh SorathiyaDepartment of In-vitro Fertilization, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: drdipeshsorathiya@gmail.com.
Vivek NandaDepartment of Emergency Medicine, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad,382421, Gujarat, India. Electronic address: dr.viveknanda@gmail.com.
Parin MehtaDepartment of Ophthalmology, Kusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: parinmehta23@gmail.com.
Adit DesaiKusum Dhirajlal Hospital, Vaishnodevi Circle, SG Road, Ahmedabad, 382421, Gujarat, India. Electronic address: adit@kdhospital.co.in.
Sir Sunderlal Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo comparatively evaluate ICU requirement, length of stay, and mortality between single-dose vaccinated and non-vaccinated hospitalized COVID-19 patients.

designA retrospective observational study was carried out in a tertiary care hospital in western Indian, from April 1 to June 30, 2021.

resultsOf the 569 patients who fulfilled the eligibility criteria and were enrolled in the study, 137 (24.08%) patients had received a single dose of ChAdOx1 nCoV-19 vaccine, while 432 (75.92%) patients had not received any form of vaccination. The overall length of stay in hospital was similar for both groups; however, a significant difference was seen in length of stay in the ward and in the ICU. Vaccinated patients were admitted to the ward for 6.21 ± 3.204 days, while non-vaccinated patients were admitted for 5.56 ± 4.55 days (p < 0.001). The mean length of ICU stay for the 21 vaccinated patients requiring intensive care was 4.47 ± 2.3 days, while that for the 145 non-vaccinated patients was 6.29 ± 2.19 days (p < 0.001). Mortality was observed in four patients in the vaccinated group and in 95 patients in the non-vaccinated group.

conclusionA single dose of ChAdOx1 nCoV-19 vaccine was associated with a significantly lower severity of SARS-CoV-2 infection compared with no vaccination.

Indexed as

ChAdOx1 nCoV-19COVID-19COVID-19 VaccinesHumansIntensive Care UnitsLength of StayObservational Studies as TopicSARS-CoV-2Tertiary Care CentersVaccinationChAdOx1 nCoV-19COVID-19 VaccinesChAdOx1 nCoV-19 vaccineCOVID-19SARS-CoV-2 infectionvaccinationvaccine hesitancy

Identifiers

PMID34688949
PMCPMC8529545
OpenAlexW3205274680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.