Evidence map›Paper›PMID 34688614›Full record

ArticleThe Journal of investigative dermatology2022

State of Residency: Microbial Strain Diversity in the Skin.

Heidi H Kong, Julia Oh

Abstract read
In one paragraph

Article in The Journal of investigative dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Heidi H KongNational Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Julia OhThe Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA. Electronic address: julia.oh@jax.org.

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Anna Karolina Palucka · 1985 to 2026
$61.9M
Technology Development Project - Increasing the complexity of ex vivo human airway models for studying immune response to viral infectionU19AI142733 · NIAID · JACKSON LABORATORY · PI Adolfo Garcia-Sastre, Anna Karolina Palucka · 2019 to 2026
$23.1M
Studies of human microbes and potential perturbationsZIAAR041219 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KONG, HEIDI · 2022 to 2025
$4.3M
Metagenomes to Therapeutics: Defining the Rules for Engineering the Skin MicrobiomeDP2GM126893 · NIGMS · JACKSON LABORATORY · PI OH, JULIA · 2017 to 2017
$2.8M
Molecular Mechanisms of Staphylococcus Epidermidis Strain DiversityR01AR078634 · NIAMS · JACKSON LABORATORY · PI OH, JULIA · 2021 to 2025
$2.5M
Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis PatientsZIAAR041217 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KONG, HEIDI · 2022 to 2023
$1.2M
Microbiome Plasticity and Pathogenicity in Older Adults: Baselines and Transitions from Skilled Nursing CareR56AG060746 · NIA · JACKSON LABORATORY · PI KUCHEL, GEORGE A, OH, JULIA · 2019 to 2019
$779k
Skin Microbiome of Monogenic Skin DisordersR21AR075174 · NIAMS · JACKSON LABORATORY · PI OH, JULIA · 2019 to 2022
$466k
Community organizing: Harnessing the interactions of the microbiome as a basis for novel therapeutic strategiesK22AI119231 · NIAID · JACKSON LABORATORY · PI OH, JULIA · 2016 to 2017
$270k
NCI NIH HHS P30 CA034196NIAID NIH HHS K22 AI119231NIAID NIH HHS U19 AI142733NIAMS NIH HHS R01 AR078634NIAMS NIH HHS R21 AR075174NIA NIH HHS R56 AG060746NIGMS NIH HHS DP2 GM126893
6 · The paper itself

Abstract

Human skin hosts a diversity of microbiota. Advances in sequencing and analytical methods have increasingly illuminated the importance of the finest resolution in understanding the genetic diversity of the skin microbiota, highlighting strain-level differences and their functional implications. Such genetic diversity, which exists within an individual and is strongly individual specific underscores the difficulty in elucidating functionality. Integrated investigations of the microbial strain diversity through sequencing and culture-based approaches with host immunology and physiology will be critical in expanding our understanding of the roles of the skin microbiome.

Indexed as

Internship and ResidencyMicrobiotaHumansSkin

Identifiers

PMID34688614
PMCPMC9021319

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.