Evidence map›Paper›PMID 34688407›Full record

ArticleThe Journal of investigative dermatology2021

Making Lemonade: Putting the Wisdom of the Genome to Work in Atopic Dermatitis.

Zhaolin Zhang, James T Elder

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zhaolin ZhangDepartment of Dermatology, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan, USA.
James T ElderDepartment of Dermatology, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA. Electronic address: jelder@umich.edu.
University of Michigan · US

Funding

Linkage analysis of familial psoriasis(Supplement)R01AR042742 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD · 1994 to 2021
$10.1M
Genetic and Genomic Dissection of Psoriatic ArthritisR01AR063611 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD, GLADMAN, DAFNA D · 2012 to 2023
$6.2M
TRAINING PROGRAM IN CELL AND MOLECULAR DERMATOLOGYT32AR007197 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JAMES TILFORD ELDER, Sunny Y Wong · 1986 to 2026
$4.2M
Functional Genomics of PsoriasisR01AR065183 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD · 2013 to 2016
$1.7M
NIAMS NIH HHS R01 AR042742NIAMS NIH HHS R01 AR063611NIAMS NIH HHS R01 AR065183NIAMS NIH HHS T32 AR007197
6 · The paper itself

Abstract

Getting from a GWAS hit to an actionable gene remains a challenge in complex disease genetics. In a new article of the Journal of Investigative Dermatology, Sobczyk et al. (2021) use a wide variety of genomic data to generate a prioritization algorithm to tackle this problem in atopic dermatitis, calling on the wisdom of the genome to generate promising results.

Indexed as

Dermatitis, AtopicEczemaGenome-Wide Association StudyHumans

Identifiers

PMID34688407
PMCPMC8594458
OpenAlexW3206645989

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.