Evidence map›Paper›PMID 34688231›Full record

ReviewSingapore medical journal2023

Coronavirus disease 2019 in kidney transplant recipients: a systematic review and meta-analysis.

Quan Yao Ho, Rehena Sultana, Tung Lin Lee, Sobhana Thangaraju, Terence Kee, Htay Htay

Open access · diamondAbstract readReview
In one paragraph

Review in Singapore medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Kidney involvement and anemia in COVID-19 infection.World journal of nephrology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Quan Yao HoDepartment of Renal Medicine, Singapore General Hospital; SingHealth Duke-NUS Transplant Centre, Singapore.
Rehena SultanaDuke-NUS Medical School, Singapore.
Tung Lin LeeDepartment of Renal Medicine, Singapore General Hospital, Singapore.
Sobhana ThangarajuDepartment of Renal Medicine, Singapore General Hospital; SingHealth Duke-NUS Transplant Centre, Singapore.
Terence KeeDepartment of Renal Medicine, Singapore General Hospital; SingHealth Duke-NUS Transplant Centre, Singapore.
Htay HtayDepartment of Renal Medicine, Singapore General Hospital; Duke-NUS Medical School, Singapore.
Singapore General Hospital · SGDuke-NUS Medical School · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The clinical presentation and outcomes of coronavirus disease 2019 (COVID-19) in kidney transplant recipients (KTRs) have not been well studied. Methods: We performed a meta-analysis to examine the presenting features, outcomes and the effect of treatment on outcomes of KTRs with COVID-19. Database search was performed up to 5 September 2020 through PubMed, Embase, Web of Science, Scopus and CENTRAL. Results: Overall, 23 studies (1,373 patients) were included in the review and meta-analysis. The most common presenting symptoms included fever (74.0%, 95% confidence interval [CI] 65.3-81.1), cough (63.3%, 95% CI 56.5-69.6) and dyspnoea (47.5%, 95% CI 39.6-55.6). Pooled rates of mortality and critical illness were 21.1% (95% CI 15.3-28.4) and 27.7% (95% CI 21.5-34.8), respectively. Acute kidney injury occurred in 38.9% (95% CI 30.6-48.1) and dialysis was required in 12.4% (95% CI 8.3-18.0) of the cases. Conclusion: Kidney transplant recipients with COVID-19 have a similar clinical presentation as the general population, but they have higher morbidity and mortality. It is uncertain whether high-dose corticosteroid or hydroxychloroquine reduces the risks of mortality in KTRs with COVID-19.

Indexed as

Coronavirus disease 2019COVID-19kidney transplantationmeta-analysissystematic review

Identifiers

PMID34688231
PMCPMC10645004
OpenAlexW3208640696

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.