Evidence map›Paper›PMID 34688038›Full record

ReviewCurrent opinion in microbiology2021

Antibacterial particles and predatory bacteria as alternatives to antibacterial chemicals in the era of antibiotic resistance.

Richard P Novick

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Frontiers in microbiology · 2026
    Article
  2. Frontiers in microbiology · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Richard P NovickNYU Grossman School of Medicine, New York, NY 10016, USA. Electronic address: rchard.novick@med.nyu.
New York University · US

Funding

Converting staphylococcal pathogenicity islands from malevolence to benevolenceR01AI139613 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NOVICK, RICHARD P. · 2019 to 2023
$4.0M
NIAID NIH HHS R01 AI139613
6 · The paper itself

Abstract

This review is focused on the subset of antibacterial agents whose action involves one-on-one targeting of infecting bacteria. These agents target individual bacteria and their efficacy is based on particle numbers in contrast to chemical agents such as antibiotics, whose efficacy is based on minimal inhibitory concentrations. Four extant members of this class are predatory bacteria, functional (plaque-forming) phages, and engineered particulate systems, phagemids (plasmids that contain a phage packaging signal) and antibacterial drones (ABDs) that package chromosomal island DNA carrying antibacterial genes. We differentiate the natural predators, phages and predatory bacteria, from the engineered delivery vehicles, phagemids and ABDs, because the latter are much more versatile and can largely bypass the historical warfare that informs the predator-prey interactions.

Indexed as

BacteriophagesUnmanned Aerial DevicesAnti-Bacterial AgentsBacteriaDrug Resistance, MicrobialAnti-Bacterial Agents

Identifiers

PMID34688038
PMCPMC8665672
OpenAlexW3208193340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.