ArticleFree radical biology & medicine2021
Complexities of the chemogenetic toolkit: Differential mDAAO activation by d-amino substrates and subcellular targeting.
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Article in Free radical biology & medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- Chemogenetic Manipulation of HPrecision chemistry · 2026Article
- An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems.Nature communications · 2025Article
- Prolonged In Vivo Chemogenetic Generation of Hydrogen Peroxide by Endothelial Cells Induces Cardiac Remodelling and Vascular Dysfunction.Antioxidants (Basel, Switzerland) · 2025Article
- Fundamentals of redox regulation in biology.Nature reviews. Molecular cell biology · 2024Review
- Ten "Cheat Codes" for Measuring Oxidative Stress in Humans.Antioxidants (Basel, Switzerland) · 2024Review
- Mitochondrial HNature communications · 2024Article
- The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine.Frontiers in pharmacology · 2024Article
- 50 shades of oxidative stress: A state-specific cysteine redox pattern hypothesis.Redox biology · 2023Article
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 6 countries.
Yusuf C ErdoganMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Hamza Y AltunMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Melike SecilmisMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Busra N AtaMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Gulsah SevimliMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Zeynep CoklukMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Asal Ghaffari ZakiMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Serap SezenMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Tuba Akgul CaglarResearch Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul, Turkey.
İlker SevgenMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.
Benjamin SteinhornDivision of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Huiwang AiDepartment of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
Gürkan ÖztürkResearch Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul, Turkey; Physiology Department, International School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Vsevelod V BelousovFederal Center of Brain Research and Neurotechnologies, Federal Medical Biological Agency, 117997, Moscow, Russia; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997, Moscow, Russia; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, 117997, Moscow, Russia; Institute of Cardiovascular Physiology, Universitätsmedizin Göttingen, 37073, Göttingen, Germany.
Thomas MichelDivision of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: thomas_michel@hms.harvard.edu.
Emrah ErogluMolecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey; Research Institute for Health Sciences and Technologies (SABITA), Istanbul Medipol University, Istanbul, Turkey; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Austria; Nanotechnology Research and Application Center, Sabanci University, Istanbul, Turkey. Electronic address: emrah.eroglu@sabanciuniv.edu.
Sabancı Üniversitesi · TRBrigham and Women's Hospital · USIstanbul Medipol University · TRPirogov Russian National Research Medical University · RUUniversity of Virginia · US
Funding
Chemogenetic Neurovascular Oxidative Stress: Neurodegeneration and Cardiac RemodelingR01NS131182 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI Thomas Michel · 2024 to 2026
$2.3MHydrogen peroxide in endothelial function and dysfunctionR01HL152173 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHEL, THOMAS · 2021 to 2024
$2.2MDynamic tissue-specific modulation of redox stress using chemogeneticsR33HL157918 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHEL, THOMAS · 2021 to 2022
$1.0MChemogenetic approaches to define the roles of redox dysfunction in the cardiomyopathy of agingR21AG063073 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHEL, THOMAS · 2019 to 2020
$480kNHLBI NIH HHS R01 HL152173NHLBI NIH HHS R33 HL157918NIA NIH HHS R21 AG063073NINDS NIH HHS R01 NS131182
Abstract
A common approach to investigate oxidant-regulated intracellular pathways is to add exogenous H
Indexed as
Hydrogen PeroxideOxidantsAmino AcidsCells, CulturedOxidation-ReductionAmino AcidsHydrogen PeroxideOxidantsD-amino Acid oxidase (DAAO) catalysis and targetingd-amino acidsGenetically encoded biosensorshsGFPHydrogen peroxideHydrogen sulfideHyPer7Multiparametric imaging
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.