Evidence map›Paper›PMID 34687568›Full record

ArticleJournal of applied microbiology2022

Biosynthesis of γ-aminobutyric acid by lactic acid bacteria in surplus bread and its use in bread making.

Michela Verni, Anna Vekka, Mikko Immonen, Kati Katina, Carlo Giuseppe Rizzello, Rossana Coda

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. ValorizingMicroorganisms · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Michela VerniDepartment of Soil, Plant and Food Science, University of Bari "Aldo Moro", Bari, Italy.ORCID https://orcid.org/0000-0001-6767-5035
Anna VekkaDepartment of Food and Nutrition Sciences, University of Helsinki, Helsinki, Finland.
Mikko ImmonenDepartment of Food and Nutrition Sciences, University of Helsinki, Helsinki, Finland.
Kati KatinaDepartment of Food and Nutrition Sciences, University of Helsinki, Helsinki, Finland.
Carlo Giuseppe RizzelloDepartment of Environmental Biology, "Sapienza" University of Rome, Rome, Italy.
Rossana CodaDepartment of Food and Nutrition Sciences, University of Helsinki, Helsinki, Finland.
University of Helsinki · FISapienza University of Rome · ITUniversity of Bari Aldo Moro · IT

Funding

Euro Trans Bio 2017-2019
6 · The paper itself

Abstract

aimsThe aim of this study was to investigate the effectiveness of bread as substrate for γ-aminobutyric acid (GABA) biosynthesis, establishing a valorization strategy for surplus bread, repurposing it within the food chain. METHODS AND

resultsSurplus bread was fermented by lactic acid bacteria (LAB) to produce GABA. Pediococcus pentosaceus F01, Levilactobacillus brevis MRS4, Lactiplantibacillus plantarum H64 and C48 were selected among 33 LAB strains for the ability to synthesize GABA. Four fermentation experiments were set up using surplus bread as such, added of amylolytic and proteolytic enzymes, modifying the pH or mixed with wheat bran. Enzyme-treated slurries led to the release of glucose (up to 20 mg g

conclusionsBesides the high GABA concentration (148 mg kg SIGNIFICANCE AND IMPACT OF STUDY: Our results represent a proof of concept of effective strategies to repurpose food industry side streams.

Indexed as

BreadLactobacillalesDietary FiberFermentationFood Microbiologygamma-Aminobutyric AcidDietary Fibergamma-Aminobutyric Acidbioprocessingenzymesfermentationfoodlactic acid bacteria

Identifiers

PMID34687568
PMCPMC9544796
OpenAlexW3210033853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.