Evidence map›Paper›PMID 34687162›Full record

ArticleESC heart failure2021

The kinocardiograph for assessment of changes in haemodynamic load in patients with chronic heart failure with reduced ejection fraction.

Cyrille Herkert, Pierre-François Migeotte, Amin Hossein, Rudolph Ferdinand Spee, Hareld Marijn Clemens Kemps

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Cyrille HerkertDepartment of Cardiology, Máxima Medical Centre, Dominee Theodor Fliednerstraat 1, Eindhoven, 5631 BM, The Netherlands.ORCID 0000-0002-1191-8322
Pierre-François MigeotteLPHYS, Université Libre de Bruxelles, Brussels, Belgium.
Amin HosseinLPHYS, Université Libre de Bruxelles, Brussels, Belgium.
Rudolph Ferdinand SpeeDepartment of Cardiology, Máxima Medical Centre, Dominee Theodor Fliednerstraat 1, Eindhoven, 5631 BM, The Netherlands.
Hareld Marijn Clemens KempsDepartment of Cardiology, Máxima Medical Centre, Dominee Theodor Fliednerstraat 1, Eindhoven, 5631 BM, The Netherlands.
Radboud University Nijmegen · NLUniversité Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe kinocardiograph (KCG) is an unobtrusive device, consisting of a chest sensor, which records local thoracic vibrations produced in result of cardiac contraction and ejection of blood into the great vessels [seismocardiography (SCG)], and a lower back sensor, which records micromovements of the body in reaction to blood flowing through the vasculature [ballistocardiography (BCG)]. SCG and BCG signals are translated to the integral of cardiac kinetic energy (iK) and cardiac maximum power (Pmax), which might be promising metrics for future telemonitoring purposes in heart failure (HF). As a first step of validation, this study aimed to determine whether iK and Pmax are responsive to exercise-induced changes in the haemodynamic load of the heart in HF patients. METHODS AND

resultsFifteen patients with stable HF with reduced ejection fraction performed a submaximal exercise protocol. KCG and cardiac ultrasound measurements were obtained both at rest and at submaximal exercise. BCG iK over the cardiac cycle (CC) increased significantly (0.0026 ± 0.0017 to 0.0052 ± 0.0061 mJ.s.; P = 0.01) during exercise, in contrast to a non-significant increase in SCG iK CC. BCG Pmax CC increased significantly (0.92 ± 0.89 to 2.03 ± 1.95 mJ/s; P = 0.02), in contrast to a non-significant increase in SCG Pmax CC. When analysing the systolic phase of the CC, similar patterns were found. Cardiac output (CO) ratio (i.e. CO exercise/CO rest) showed a moderate, significant correlation with BCG Pmax CC ratio (r = +0.65; P = 0.008) and with SCG Pmax CC ratio (r = +0.54; P = 0.04).

conclusionsiK and Pmax measured with the KCG, preferentially using BCG, are responsive to changes in the haemodynamic load of the heart in HF patients. The combination of the BCG and SCG sensor might be of added value to fully understand changes in haemodynamics and to discriminate between an HF patient and a healthy individual.

Indexed as

BallistocardiographyHeart FailureHemodynamicsHumansMyocardial ContractionStroke VolumeBallistocardiographyChronic heart failureHemodynamic loadKinetic energySeismocardiography

Identifiers

PMID34687162
PMCPMC8712789
OpenAlexW3207788611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.