ReviewJournal of the Association for Research in Otolaryngology : JARO2021
Too Blind to See the Elephant? Why Neuroscientists Ought to Be Interested in Tinnitus.
Review in Journal of the Association for Research in Otolaryngology : JARO, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- Review
- A Unified Theory for the Development of Tinnitus Perception and Hyperacusis Based on Associative Plasticity in the Dorsal Cochlear Nucleus.Brain sciences · 2026Article
- A large-scale, multi-site examination of resting state functional connectivity in tinnitus.Scientific reports · 2025Article
- Breathing Rate as a Marker for Noise-Induced Stress in Guinea Pigs.Brain sciences · 2025Article
- Candidate Key Proteins in Tinnitus-A Bioinformatic Study of Synaptic Transmission in the Inferior Colliculus.International journal of molecular sciences · 2025Article
- Candidate Key Proteins in Tinnitus-A Bioinformatic Study of Synaptic Transmission in the Cochlear Nucleus.Biomedicines · 2024Article
- Predictive coding and stochastic resonance as fundamental principles of auditory phantom perception.Brain : a journal of neurology · 2023Review
- Disruptions of default mode network and precuneus connectivity associated with cognitive dysfunctions in tinnitus.Scientific reports · 2023Article
- Comparative Transcriptomic Analysis of Archival Human Vestibular Schwannoma Tissue from Patients with and without Tinnitus.Journal of clinical medicine · 2023Article
- The corticofugal oscillatory modulation of the cochlear receptor during auditory and visual attention is preserved in tinnitus.Frontiers in neural circuits · 2023Article
- Differential cortical activation patterns: pioneering sub-classification of tinnitus with and without hyperacusis by combining audiometry, gamma oscillations, and hemodynamics.Frontiers in neuroscience · 2023Article
- Conversations in Cochlear Implantation: The Inner Ear Therapy of Today.Biomolecules · 2022Review
- Recent-onset and persistent tinnitus: Uncovering the differences in brain activities using resting-state functional magnetic resonance imaging technologies.Frontiers in neuroscience · 2022Article
- Fear influences phantom sound percepts in an anechoic room.Frontiers in psychology · 2022Article
- Disturbed Balance of Inhibitory Signaling Links Hearing Loss and Cognition.Frontiers in neural circuits · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A curative therapy for tinnitus currently does not exist. One may actually exist but cannot currently be causally linked to tinnitus due to the lack of consistency of concepts about the neural correlate of tinnitus. Depending on predictions, these concepts would require either a suppression or enhancement of brain activity or an increase in inhibition or disinhibition. Although procedures with a potential to silence tinnitus may exist, the lack of rationale for their curative success hampers an optimization of therapeutic protocols. We discuss here six candidate contributors to tinnitus that have been suggested by a variety of scientific experts in the field and that were addressed in a virtual panel discussion at the ARO round table in February 2021. In this discussion, several potential tinnitus contributors were considered: (i) inhibitory circuits, (ii) attention, (iii) stress, (iv) unidentified sub-entities, (v) maladaptive information transmission, and (vi) minor cochlear deafferentation. Finally, (vii) some potential therapeutic approaches were discussed. The results of this discussion is reflected here in view of potential blind spots that may still remain and that have been ignored in most tinnitus literature. We strongly suggest to consider the high impact of connecting the controversial findings to unravel the whole complexity of the tinnitus phenomenon; an essential prerequisite for establishing suitable therapeutic approaches.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.