ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022
The impact of obesity on postoperative outcomes in colorectal cancer patients: a retrospective database study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 20 citations in OpenAlex.
- Do Obesity Classifications Create the Obesity Paradox? A Scoping Review of Obesity Definitions Applied in Sepsis Research.Clinical obesity · 2026Article
- Preoperative body composition measured by bioelectrical impedance analysis can predict pancreatic fistula after pancreatic surgery.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Article
- Article
- Laparoscopic versus open colectomy for locally advanced colon cancer in obese patients: a nationwide, multicenter, propensity score-based analysis of short- and long-term outcomes.Japanese journal of clinical oncology · 2025Article
- Evaluating body mass index's impact on Da Vinci Robotic rectal cancer surgery, a retrospective study.Journal of robotic surgery · 2024Article
- The Relationship Between BMI and Postoperative Complications Among Colorectal Cancer Patients Undergoing Surgery.Cureus · 2023Article
- Predictive modeling based on tumor spectral CT parameters and clinical features for postoperative complications in patients undergoing colon resection for cancer.Insights into imaging · 2023Article
- Analysis of factors associated with postoperative acute kidney injury in patients with colorectal cancer and the development of a risk prediction model: a retrospective study.Updates in surgery · 2023Article
- Laparoscopic versus robotic adrenalectomy in severely obese patients.Surgical endoscopy · 2023Article
- Laparoscopy and laparotomy for patients with transverse colon cancer: comparative analysis of short-term surgical outcomes.American journal of translational research · 2023Article
- The associations between lipid profiles and visceral obesity among gastrointestinal cancer patients: a cross-sectional study.Lipids in health and disease · 2022Observational
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6 authors at 3 institutions in 1 country.
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Abstract
purposeObesity is an independent risk factor for worse outcomes in various surgical settings. Whether obesity is a prognostic factor for postoperative morbidity and mortality of colorectal cancer (CRC) is inconclusive. This study aimed to determine the impact of obesity on short-term postoperative outcomes in CRC patients undergoing laparoscopic surgery.
methodsData of a total of 23,898 CRC patients aged ≥ 20 years and undergoing laparoscopic resection were extracted from the US National Inpatient Sample (NIS) database and analyzed. The study endpoints were in-hospital mortality, any postoperative complications, infection/sepsis, acute kidney injury (AKI), deep vein thrombosis (DVT)/pulmonary embolisms (PE), and extended hospital stay. Univariate and multivariate logistic regression analyses were performed to examine the associations between patients' obesity status (morbid obese: BMI > = 40 kg/m
resultsIn 23,898 CRC patients undergoing laparoscopic resection, the prevalence of obesity prevalence was 11.8%. After adjustment, the results revealed that morbid obesity was significantly associated with increased risk for in-hospital mortality (aOR = 2.06, 95%CI: 1.11-3.83), AKI (aOR = 1.78, 95%CI = 1.34-2.36), DVT/PE (aOR = 2.88, 95%CI = 1.70-4.88), and extended LOS (aOR = 1.21, 95%CI = 1.02-1.43), while non-morbid obesity was significantly associated with more DVT/PE (aOR = 2.12, 95%CI = 1.32-3.41) as compared with non-obesity.
conclusionIn patients with CRC undergoing laparoscopic surgery, morbid obesity is strongly associated with worse postoperative outcomes, including increased in-hospital mortality, postoperative AKI and DVT/PE, and extended LOS. The findings of the present study highlight the importance of obesity status in risk stratification for laparoscopic CRC surgery.
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