Evidence map›Paper›PMID 34686893›Full record

ReviewHuman genetics2022

A review of migraine genetics: gathering genomic and transcriptomic factors.

Andreia Dias, Tiago Mariz, Alda Sousa, Carolina Lemos, Miguel Alves-Ferreira

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Novel Potential Risk Loci for Migraine in the Portuguese Population.International journal of molecular sciences · 2026
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Andreia DiasUnIGENe, i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.
Tiago MarizICBAS, Instituto Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.
Alda SousaUnIGENe, i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.
Carolina LemosUnIGENe, i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.
Miguel Alves-FerreiraUnIGENe, i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal. miguel.ferreira@ibmc.up.pt.ORCID http://orcid.org/0000-0002-4275-9598
Universidade do Porto · PT

Funding

Fundação para a Ciência e a Tecnologia PTDC/MEC-NEU/29486/2017Interreg MIGRAINEE
6 · The paper itself

Abstract

Migraine is a common and complex neurologic disorder that affects approximately 15-18% of the general population. Although the cause of migraine is unknown, some genetic studies have focused on unravelling rare and common variants underlying the pathophysiological mechanisms of this disorder. This review covers the advances in the last decade on migraine genetics, throughout the history of genetic methodologies used, including recent application of next-generation sequencing techniques. A thorough review of the literature interweaves the genomic and transcriptomic factors that will allow a better understanding of the mechanisms underlying migraine pathophysiology, concluding with the clinical utility landscape of genetic information and future consideration to creating a new frontier toward advancing the field of personalized medicine.

Indexed as

Genetic Predisposition to DiseaseGenomicsTranscriptomeBiomarkersGenetic VariationGenome-Wide Association StudyHumansMigraine DisordersPrecision MedicineBiomarkers

Identifiers

PMID34686893
OpenAlexW3207939390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.