SynthesisScientific reports2021
Meta-analysis of the normal diffusion tensor imaging values of the median nerve and how they change in carpal tunnel syndrome.
Synthesis in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- White matter abnormalities in tuberous sclerosis complex: a systematic review of diffusion tensor imaging studies.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Meta-analysis of the normal diffusion tensor imaging values of the peripheral nerves in the upper limb.Scientific reports · 2023Pooled it
- The Association Between Changes in White Matter Microstructure and Cognitive Function in Older Adults with Mild Cognitive Impairment.Brain sciences · 2026Article
- Electrophysiological analysis of distal, proximal, and dual compression of the median nerve.IBRO neuroscience reports · 2025Article
- Article
- Evaluation of diffusion tensor imaging in foraminal cervical nerve and fiber bundle reconstruction in patients with cervical spondylotic radiculopathy.Japanese journal of radiology · 2025Article
- Diagnostic Dilemmas in Carpal Tunnel Syndrome and Cervical Spine Disorders: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2025Review
- Combination of morphological and multiparametric MR neurography enhances carpal tunnel syndrome diagnosis and evaluation.Scientific reports · 2025Article
- Diffusion tensor imaging in peroneal neuropathy: a prospective, single-centre study.BMJ neurology open · 2025Article
- Outcome Prediction by Diffusion Tensor Imaging (DTI) in Patients with Traumatic Injuries of the Median Nerve.Neurology international · 2024Article
- Advances in Imaging of Compressive Neuropathies.Hand clinics · 2024Review
- Comparison of distortion correction preprocessing pipelines for DTI in the upper limb.Magnetic resonance in medicine · 2024Article
- Diffusion tensor imaging combined with the dual-echo steady-state (DESS) protocol for the evaluation of the median nerve in the carpal tunnel: A preliminary study.Surgical neurology international · 2024Article
- Future Considerations in the Diagnosis and Treatment of Compressive Neuropathies of the Upper Extremity.Journal of hand surgery global online · 2023Review
- Correlation between diffusion tensor indices and fascicular morphometric parameters of peripheral nerve.Frontiers in physiology · 2023Article
- Quantitative parameters of diffusion tensor imaging in the evaluation of carpal tunnel syndrome.Quantitative imaging in medicine and surgery · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Carpal tunnel syndrome (CTS) leads to distortion of axonal architecture, demyelination and fibrosis within the median nerve. Diffusion tensor imaging (DTI) characterises tissue microstructure and generates reproducible proxy measures of nerve 'health' which are sensitive to myelination, axon diameter, fiber density and organisation. This meta-analysis summarises the normal DTI values of the median nerve, and how they change in CTS. This systematic review included studies reporting DTI of the median nerve at the level of the wrist in adults. The primary outcome was to determine the normal fractional anisotropy (FA) and mean diffusivity (MD) of the median nerve. Secondarily, we show how the FA and MD differ between asymptomatic adults and patients with CTS, and how these differences are independent of the acquisition methods. We included 32 studies of 2643 wrists, belonging to 1575 asymptomatic adults and 1068 patients with CTS. The normal FA was 0.58 (95% CI 0.56, 0.59) and the normal MD was 1.138 × 10
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