Evidence map›Paper›PMID 34686697›Full record

ArticleScientific reports2021

Swim training affects Akt signaling and ameliorates loss of skeletal muscle mass in a mouse model of amyotrophic lateral sclerosis.

Karol Cieminski, Damian Jozef Flis, Katarzyna Dzik, Jan Jacek Kaczor, Emilia Czyrko, Malgorzata Halon-Golabek, Mariusz Roman Wieckowski, Jedrzej Antosiewicz, Wieslaw Ziolkowski

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Skeletal muscle dysfunction in amyotrophic lateral sclerosis: a mitochondrial perspective and therapeutic approaches.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Karol CieminskiPoznan University of Physical Education, Poznan, Poland.
Damian Jozef FlisDepartment of Physiology and Biochemistry, Gdansk University of Physical Education and Sport, 80-336, Gdansk, Poland. damian.flis@gumed.edu.pl.
Katarzyna DzikDepartment of Physiology and Biochemistry, Gdansk University of Physical Education and Sport, 80-336, Gdansk, Poland.
Jan Jacek KaczorDepartment of Physiology and Biochemistry, Gdansk University of Physical Education and Sport, 80-336, Gdansk, Poland.
Emilia CzyrkoPoznan University of Physical Education, Poznan, Poland.
Malgorzata Halon-GolabekDepartment of Physiotherapy, Faculty of Health Sciences Medical, University of Gdansk, Gdansk, Poland.
Mariusz Roman WieckowskiLaboratory of Mitochondrial Biology and Metabolism, Nencki Institute of Experimental Biology, Warsaw, Poland.
Jedrzej AntosiewiczDepartment of Bioenergetics and Physiology of Exercise, Faculty of Health Sciences, Medical University of Gdansk, Gdansk, Poland.
Wieslaw ZiolkowskiDepartment of Rehabilitation Medicine, Faculty of Health Sciences Medical, University of Gdansk, 80-219, Gdansk, Poland. wieslaw.ziolkowski@gumed.edu.pl.
Gdańsk Medical University · PLGdansk University of Physical Education and Sport · PLInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We tested the hypothesis that swim training reverses the impairment of Akt/FOXO3a signaling, ameliorating muscle atrophy in ALS mice. Transgenic male mice B6SJL-Tg (SOD1

Indexed as

Amyotrophic Lateral SclerosisAnimalsDisease Models, AnimalForkhead Box Protein O3HumansMaleMiceMice, TransgenicMuscle, SkeletalMuscular AtrophyProto-Oncogene Proteins c-aktSignal TransductionSuperoxide Dismutase-1SwimmingTripartite Motif ProteinsForkhead Box Protein O3Proto-Oncogene Proteins c-aktSuperoxide Dismutase-1Tripartite Motif Proteins

Identifiers

PMID34686697
PMCPMC8536703
OpenAlexW3207720769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.