Evidence map›Paper›PMID 34686676›Full record

ArticleNature communications2021

Hedgehog artificial macrophage with atomic-catalytic centers to combat Drug-resistant bacteria.

Yanping Long, Ling Li, Tao Xu, Xizheng Wu, Yun Gao, Jianbo Huang, Chao He, Tian Ma, Lang Ma, Chong Cheng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 156 citations in OpenAlex.

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  17. Review
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  19. Artificial Neutrophils Against Vascular Graft Infection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  20. Glucose Responsive Coacervate Protocells from Microfluidics for Diabetic Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Yanping LongCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, 610065, Chengdu, China.ORCID 0000-0001-7313-6679
Ling LiDepartment of Ultrasound, West China Hospital, Sichuan University, 610041, Chengdu, China.ORCID 0000-0002-7069-236X
Tao XuCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, 610065, Chengdu, China.ORCID 0000-0002-6897-5993
Xizheng WuCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, 610065, Chengdu, China.ORCID 0000-0001-5618-4185
Yun GaoCollege of Biomass Science and Engineering, Textile Institute, Sichuan University, 610065, Chengdu, China.ORCID 0000-0002-0923-8088
Jianbo HuangDepartment of Ultrasound, West China Hospital, Sichuan University, 610041, Chengdu, China.ORCID 0000-0002-0265-7917
Chao HeCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, 610065, Chengdu, China.ORCID 0000-0002-3259-3176
Tian MaDepartment of Ultrasound, West China Hospital, Sichuan University, 610041, Chengdu, China.
Lang MaDepartment of Ultrasound, West China Hospital, Sichuan University, 610041, Chengdu, China.ORCID 0000-0003-3741-1885
Chong ChengCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, 610065, Chengdu, China. chong.cheng@scu.edu.cn.ORCID 0000-0002-6872-2240
Changsheng ZhaoCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, 610065, Chengdu, China. zhaochsh70@scu.edu.cn.ORCID 0000-0002-4619-3499
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic drug-resistant bacteria represent a threat to human health, for instance, the methicillin-resistant Staphylococcus aureus (MRSA). There is an ever-growing need to develop non-antibiotic strategies to fight bacteria without triggering drug resistance. Here, we design a hedgehog artificial macrophage with atomic-catalytic centers to combat MRSA by mimicking the "capture and killing" process of macrophages. The experimental studies and theoretical calculations reveal that the synthesized materials can efficiently capture and kill MRSA by the hedgehog topography and substantial generation of •O

Indexed as

MacrophagesAnimalsAnti-Bacterial AgentsBiomimetic MaterialsCatalysisDrug Resistance, BacterialMetal-Organic FrameworksMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsNanomedicineRabbitsReactive Oxygen SpeciesStaphylococcal InfectionsWound HealingAnti-Bacterial AgentsMetal-Organic FrameworksReactive Oxygen Species

Identifiers

PMID34686676
PMCPMC8536674
OpenAlexW3207331436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.