SynthesisHeart (British Cardiac Society)2022
Prognostic value of coronary computed tomography angiographic derived fractional flow reserve: a systematic review and meta-analysis.
Synthesis in Heart (British Cardiac Society), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- ESR Essentials: imaging in stable chest pain - practice recommendations by ESCR.European radiology · 2024Guideline
- Clinical practice guidelines for diagnostic and treatment of the chronic heart failure.Archivos de cardiologia de Mexico · 2024Guideline
- Sex Differences in Computed Tomography Coronary Stenosis Severity Versus Flow Impairment and Impact on Revascularization, Clinical Events and Health Care Costs: A FORECAST Substudy.Journal of the American Heart Association · 2025Trial
- Advanced quantitative CT for coronary artery disease: integrating stenosis quantification, plaque quantification, and fractional flow reserve-CT.The British journal of radiology · 2026Review
- Clinical Management Across CAD-RADS Categories in Patients with Intermediate CT-FFR.Journal of cardiovascular development and disease · 2026Article
- Sex-specific assumptions underlie cardiovascular digital twin technologies: A narrative review.PLOS digital health · 2026Review
- Great debate: the new risk factor-weighted clinical likelihood model is useful to estimate the initial pre-test probability of obstructive coronary artery disease in individuals with suspected chronic coronary syndromes.European heart journal · 2026Article
- Practical Barriers to Real-World Implementation of Artificial Intelligence-Driven CT-Derived Fractional Flow Reserve.Korean journal of radiology · 2026Article
- Molecular imaging of immune and fibrosis targets to guide therapy for repair after myocardial infarction.Nature reviews. Cardiology · 2026Review
- FFR-CT: Technical Advances and Implementation in Clinical Practice.Journal of imaging · 2026Review
- Motion compensated reconstruction improves image quality and interpretability of dual-layer coronary CT angiography.European radiology · 2026Article
- Radiomics of Pericoronary Adipose Tissue and CT-FFR to Predict Major Adverse Cardiovascular Events in Patients with T2DM Complicated by CAD.Journal of cardiovascular translational research · 2026Article
- Retrospective Analysis of Incidental Myocardial Perfusion Defects on Non-ECG-Gated Contrast-Enhanced CT in Emergency Settings.Medicina (Kaunas, Lithuania) · 2026Article
- Multimodality Imaging Approach in Diagnosis and Follow-Up of Aortic Coarctation in Adulthood.Journal of clinical medicine · 2026Review
- Prognostic Value of a Coronary Computed Tomography Angiography-Derived Ischemia Algorithm: Comparison Against Hybrid Coronary Computed Tomography Angiography/Positron Emission Tomography Imaging.Journal of the American Heart Association · 2025Observational
- Review
- Assessment of non-alcoholic fatty liver disease in suspected coronary artery disease patients: prognostic value and incremental predictive utility over cardiovascular risk factors and CCTA.BMC medical imaging · 2025Article
- [Application advances of fractional flow reserve in endovascular treatment of lower-extremity arterial disease].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- The role of cardiac imaging in the post-ISCHEMIA world.The British journal of radiology · 2025Review
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
objectivesTo obtain more powerful assessment of the prognostic value of fractional flow reserve
methodsWe searched PubMed and Web of Science electronic databases for published studies that evaluated clinical outcomes following fractional flow reserve
resultsFive studies were identified including a total of 5460 patients eligible for meta-analyses. The primary endpoint occurred in 60 (1.1%) patients, 0.6% (13/2126) with FFR
conclusionsThe 12-month outcomes in patients with stable CAD show low rates of events in those with a negative FFR
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.