Evidence map›Paper›PMID 34686542›Full record

ArticleJournal for immunotherapy of cancer2021

Sarah Boughdad, Sofiya Latifyan, Craig Fenwick, Hasna Bouchaab, Madeleine Suffiotti, Javid J Moslehi, Joe-Elie Salem, Niklaus Schaefer, Marie Nicod-Lalonde, Julien Costes and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 72 citations in OpenAlex.

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  8. How to Use Multimodality Imaging in Cardio-Oncology.Journal of cardiovascular development and disease · 2026
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  14. False Positive Findings ofMolecular imaging and radionuclide therapy · 2025
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  16. A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Sarah BoughdadNuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0003-1900-758X
Sofiya LatifyanDepartment of Medical Oncology, Lausanne University Hospital, Lausanne, Switzerland.
Craig FenwickImmunology and allergy division, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Hasna BouchaabDepartment of Medical Oncology, Lausanne University Hospital, Lausanne, Switzerland.
Madeleine SuffiottiImmunology and allergy division, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Javid J MoslehiSection of Cardio-Oncology & Immunology, Division of Cardiology and the Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, USA.
Joe-Elie SalemCardio-Oncology Program, Pitié-Salpétrière Hospital, Paris, France, AP-HP, Pitié-Salpétrière Hospital,Sorbonne, INSERM, CIC-1901, Paris, France, Paris, France, France.ORCID 0000-0002-0331-3307
Niklaus SchaeferNuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0002-9732-7696
Marie Nicod-LalondeNuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0002-4886-0611
Julien CostesRadiopharmacy Unit, Department of Pharmacy, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0002-4528-7362
Matthieu PerreauImmunology and allergy division, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Olivier MichielinDepartment of Medical Oncology, Lausanne University Hospital, Lausanne, Switzerland.
Solange PetersDepartment of Medical Oncology, Lausanne University Hospital, Lausanne, Switzerland.
John O PriorNuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0003-1429-1374
Michel ObeidImmunology and allergy division, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland michel.obeid@chuv.ch.ORCID 0000-0003-2095-2677
University of Lausanne · CHENT and Allergy · USSociety of Nuclear Medicine and Molecular Imaging · USInserm · FRUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune checkpoint inhibitor (ICI)-related myocarditis is a rare but potentially fatal adverse event that can occur following ICI exposure. Early diagnosis and treatment are key to improve patient outcomes. Somatostatin receptor-based positron emission tomography-CT (PET/CT) showed promising results for the assessment of myocardial inflammation, yet information regarding its value for the diagnosis of ICI-related myocarditis, especially at the early stage, is limited. Thus, we investigated the value of

methodsConsecutive patients with clinically suspected ICI-related myocarditis from July 2018 to February 2021 were retrospectively evaluated in this single-center study. All patients underwent imaging for the detection of ICI-related myocarditis using either cardiac magnetic resonance (CMR) imaging or

resultsA total of 11 patients had clinically suspected ICI-related myocarditis; 9 underwent

conclusionThe use of

Indexed as

AgedFemaleGallium RadioisotopesHumansImmune Checkpoint InhibitorsMaleMyocarditisPositron Emission Tomography Computed TomographyGallium RadioisotopesImmune Checkpoint Inhibitorsimmunotherapy

Identifiers

PMID34686542
PMCPMC8543755
OpenAlexW3207793918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.