Evidence map›Paper›PMID 34686002›Full record

ArticlePlants (Basel, Switzerland)2021

Screening for Selective Anticancer Activity of 65 Extracts of Plants Collected in Western Andalusia, Spain.

José Manuel Calderón-Montaño, Sara María Martínez-Sánchez, Víctor Jiménez-González, Estefanía Burgos-Morón, Emilio Guillén-Mancina, Julio José Jiménez-Alonso, Patricia Díaz-Ortega, Felipe García, Abelardo Aparicio, Miguel López-Lázaro

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Network Pharmacology and Molecular Docking ofInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Antitumor-Directed Fractionation ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Differential Biological Effects ofAntioxidants (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Synthesis,Current medicinal chemistry · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

José Manuel Calderón-MontañoDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0001-6845-797X
Sara María Martínez-SánchezDepartment of Vegetal Biology and Ecology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0001-8799-4973
Víctor Jiménez-GonzálezDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Estefanía Burgos-MorónDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Emilio Guillén-MancinaDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Julio José Jiménez-AlonsoDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Patricia Díaz-OrtegaDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Felipe GarcíaDepartment of Vegetal Biology and Ecology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Abelardo AparicioDepartment of Vegetal Biology and Ecology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Miguel López-LázaroDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0003-2794-1647

Funding

University of Seville VPPI-I.5
6 · The paper itself

Abstract

Finding cytotoxic drugs with a high selectivity towards cancer cells is crucial to improve the low survival rates of patients diagnosed with metastatic cancers. Since plants are an important source of anticancer drugs, we have screened 65 extracts from 45 plants collected in several areas of Western Andalusia (Spain) for cytotoxic activity on lung cancer cells versus lung normal cells. An extract from the leaves of

Indexed as

cancerCupressaceaelung cancerselectivityTetraclinis articulata (Vahl) Mast.

Identifiers

PMID34686002
PMCPMC8537044

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.