Evidence map›Paper›PMID 34685957›Full record

ReviewPlants (Basel, Switzerland)2021

Vegetal Compounds as Sources of Prophylactic and Therapeutic Agents in Dentistry.

Raluca-Adriana Milutinovici, Doina Chioran, Roxana Buzatu, Ioana Macasoi, Susan Razvan, Raul Chioibas, Ion Virgil Corlan, Alina Tanase, Calniceanu Horia, Ramona Amina Popovici and 5 more

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Dentistry journal · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Extracts from the Leaf ofPlants (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Review
  14. Role of Medicinal Herbs in Periodontal Therapy: A Systematic Review.Journal of International Society of Preventive & Community Dentistry
    Review
  15. Potential ofJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Raluca-Adriana MilutinoviciDepartament of Orthodontics, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, 9 Revolutiei 1989 Ave., 300070 Timisoara, Romania.
Doina ChioranDepartment of Dento-Alveolar Surgery, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, 9 Revolutiei 1989 Ave., 300070 Timisoara, Romania.
Roxana BuzatuDepartment of Facial Tooth Aesthetics, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, 9 Revolutiei 1989 Ave., 300070 Timisoara, Romania.ORCID 0000-0003-0653-0996
Ioana MacasoiDepartament of Toxicology and Drug Industry, Faculty of Pharmacy, Victor Babeș University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timișoara, Romania.
Susan RazvanDepartment of Family Medicine, Faculty of Medicine, Victor Babeș University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timișoara, Romania.
Raul ChioibasDepartment of Surgery I, Faculty of Medicine, Victor Babeș University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timișoara, Romania.
Ion Virgil CorlanDepartment of Management, Legislation and Communication in Dentistry, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
Alina TanaseDepartment of Management, Legislation and Communication in Dentistry, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
Calniceanu HoriaDepartment of Periodontics, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, 9 Revolutiei 1989 Ave., 300070 Timisoara, Romania.
Ramona Amina PopoviciDepartment of Management, Legislation and Communication in Dentistry, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
Stefania DinuDepartment of Pedodontics, Faculty of Dental Medicine, Victor Babeș University of Medicine and Pharmacy, 9 Revolutiei 1989 Ave., 300070 Timisoara, Romania.
Cristina DeheleanDepartament of Toxicology and Drug Industry, Faculty of Pharmacy, Victor Babeș University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timișoara, Romania.
Alexandra ScurtuDepartament of Toxicology and Drug Industry, Faculty of Pharmacy, Victor Babeș University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timișoara, Romania.ORCID 0000-0001-7718-4168
Iulia PinzaruDepartament of Toxicology and Drug Industry, Faculty of Pharmacy, Victor Babeș University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timișoara, Romania.ORCID 0000-0003-2295-1926
Codruta SoicaDepartament of Toxicology and Drug Industry, Faculty of Pharmacy, Victor Babeș University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timișoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental pathology remains a global health problem affecting both children and adults. The most important dental diseases are dental caries and periodontal pathologies. The main cause of oral health problems is overpopulation with pathogenic bacteria and for this reason, conventional therapy can often be ineffective due to bacterial resistance or may have unpleasant side effects. For that reason, studies in the field have focused on finding new therapeutic alternatives. Special attention is paid to the plant kingdom, which offers a wide range of plants and active compounds in various pathologies. This review focused on the most used plants in the dental field, especially on active phytocompounds, both in terms of chemical structure and in terms of mechanism of action. It also approached the in vitro study of active compounds and the main types of cell lines used to elucidate the effect and mechanism of action. Thus, medicinal plants and their compounds represent a promising and interesting alternative to conventional therapy.

Indexed as

biological activitychemical characterizationdentistryphytocompounds

Identifiers

PMID34685957
PMCPMC8537575

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.