Evidence map›Paper›PMID 34685762›Full record

ReviewCells2021

The Microenvironment's Role in Mycosis Fungoides and Sézary Syndrome: From Progression to Therapeutic Implications.

Alessandro Pileri, Alba Guglielmo, Vieri Grandi, Silvia Alberti Violetti, Daniele Fanoni, Paolo Fava, Claudio Agostinelli, Emilio Berti, Pietro Quaglino, Nicola Pimpinelli

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  14. Review
  15. Secondary lymphomas of the skin.Dermatology reports · 2024
    Review
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Alessandro PileriDermatology, IRCCS, S. Orsola-Malpighi Polyclinic, 40100 Bologna, Italy.ORCID 0000-0002-1025-7171
Alba GuglielmoDermatology, IRCCS, S. Orsola-Malpighi Polyclinic, 40100 Bologna, Italy.
Vieri GrandiSection of Dermatology, Department of Health Sciences, University of Florence, 20019 Florence, Italy.
Silvia Alberti ViolettiUOC Dermatologia, Fondazione Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Daniele FanoniUOC Dermatologia, Fondazione Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Paolo FavaDermatologic Clinic, University of Turin Medical School, 10092 Turin, Italy.
Claudio AgostinelliDepartment of Specialistic, Diagnostic and Experimental Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40100 Bologna, Italy.
Emilio BertiUOC Dermatologia, Fondazione Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Pietro QuaglinoDermatologic Clinic, University of Turin Medical School, 10092 Turin, Italy.
Nicola PimpinelliSection of Dermatology, Department of Health Sciences, University of Florence, 20019 Florence, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITUniversity of Florence · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMycosis fungoides (MF) and Sezary Syndrome (SS) are the most common cutaneous T-cell lymphomas. It has been hypothesized that the interaction between the immune system, cutaneous cells, and neoplastic elements may play a role in MF/SS pathogenesis and progression.

methodsThis paper aims to revise in a narrative way our current knowledge of the microenvironment's role in MF/SS. RESULTS AND

conclusionsLiterature data support a possible implication of microenvironment cells in MF/SS pathogenesis and progression, opening up new therapeutic avenues.

Indexed as

Disease ProgressionTumor MicroenvironmentAnimalsHumansMycosis FungoidesSezary SyndromeSkin Neoplasmscutaneouscutaneous T-cell lymphomas (CTCLs)lymphomasSezary syndrome

Identifiers

PMID34685762
PMCPMC8534987
OpenAlexW3206872386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.