Evidence map›Paper›PMID 34685671›Full record

ArticleCells2021

Antioxidant and Antiinflammatory Effects of

Stefania Merighi, Alessia Travagli, Paola Tedeschi, Nicola Marchetti, Stefania Gessi

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Multi-target protective effects ofPharmaceutical biology · 2026
    Article
  2. Article
  3. The Involvement ofNutrients · 2025
    Review
  4. OptimizedAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Antioxidants (Basel, Switzerland) · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stefania MerighiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-0839-6671
Alessia TravagliDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Paola TedeschiDepartment of Chemistry, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, Italy.
Nicola MarchettiDepartment of Chemistry, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, Italy.
Stefania GessiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
University of Ferrara · IT

Funding

University of Ferrara FIR 2019
6 · The paper itself

Abstract

backgroundWe investigated the phenolic content characterizing different plant extracts from

methodsplant samples were macerated in 40% ethanol or hot/ cold glycerate and assessed for polyphenols content. The antioxidant activity was investigated by DPPH radical scavenging assay and H

resultsPolyphenols were present in 40% ethanol plant extract, which at 0.1-10 µg/µL achieved good antioxidant effects, with a DPPH radical scavenging rate of about 90%. In LPS-stimulated cells, these plant extracts, at 1μg/μL, did not affect cell vitality, displayed significant inhibition of H

conclusion

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsCell SurvivalCHO CellsCricetulusEpilobiumHumansMacrophagesMelilotusMiceMicrogliaNitric OxidePhenolsPlant ExtractsRAW 264.7 CellsAnti-Inflammatory AgentsAntioxidantsNitric OxidePhenolsPlant ExtractsReactive Oxygen SpeciesReceptors, Adenosine A2A2A adenosine receptorflavonoidshuman healthinflammationmechanism of actionoxidative damagephenolsplant extractstannins

Identifiers

PMID34685671
PMCPMC8534520
OpenAlexW3205236281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.