Evidence map›Paper›PMID 34685660›Full record

ArticleCells2021

An Oil Hyper-Accumulator Mutant Highlights Peroxisomal ATP Import as a Regulatory Step for Fatty Acid Metabolism in

Etienne Deragon, Martin Schuler, Riccardo Aiese Cigliano, Younès Dellero, Gregory Si Larbi, Denis Falconet, Juliette Jouhet, Eric Maréchal, Morgane Michaud, Alberto Amato and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Etienne DeragonLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.
Martin SchulerLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.ORCID 0000-0003-4221-9249
Riccardo Aiese CiglianoSequentia Biotech SL, Carrer Pamplona, 08018 Barcelona, Spain.ORCID 0000-0002-9058-6994
Younès DelleroLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.ORCID 0000-0001-6038-8199
Gregory Si LarbiLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.
Denis FalconetLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.
Juliette JouhetLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.
Eric MaréchalLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.ORCID 0000-0002-0060-1696
Morgane MichaudLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.
Alberto AmatoLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.ORCID 0000-0002-9126-5535
Fabrice RébeilléLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRAE, CEDEX 9, 38054 Grenoble, France.
Centre National de la Recherche Scientifique · FRSOM Biotech (Spain) · ES

Funding

Agence Nationale de la Recherche ANR-10-LABEX-04, GRAL LabexAgence Nationale de la Recherche ANR-11-BTBR-0008, OcéanomicsAgence Nationale de la Recherche ANR-17-EURE-0003, EUR CBSBpifrance Trans'Alg
6 · The paper itself

Abstract

Thraustochytrids are marine protists that naturally accumulate triacylglycerol with long chains of polyunsaturated fatty acids, such as ω3-docosahexaenoic acid (DHA). They represent a sustainable response to the increasing demand for these "essential" fatty acids (FAs). Following an attempt to transform a strain of

Indexed as

Adenosine TriphosphateBiological TransportFatty AcidsGene Expression ProfilingGenomeModels, BiologicalMutationOilsPeroxisomesPhylogenyStramenopilesTranscriptomeAdenosine TriphosphateFatty AcidsOilslipid metabolismperoxisomal adenylate transporterthraustochytridstriacylglycerol (TAG)β-oxidationω3-docosahexaenoic acid (DHA)

Identifiers

PMID34685660
PMCPMC8534400
OpenAlexW3206768791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.