Evidence map›Paper›PMID 34685658›Full record

ArticleCells2021

Analysis of Gene Expression Patterns of Epigenetic Enzymes

Judit Vágó, Katalin Kiss, Edina Karanyicz, Roland Takács, Csaba Matta, László Ducza, Tibor A Rauch, Róza Zákány

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Judit VágóDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0003-4379-6734
Katalin KissDepartment of Medical Biology and Central Electron Microscope Laboratory, Medical School, University of Pécs, 7624 Pécs, Hungary.
Edina KaranyiczDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Roland TakácsDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Csaba MattaDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-9678-7420
László DuczaDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-2753-5748
Tibor A RauchInstitute of Biochemistry and Medical Chemistry, Medical School, University of Pécs, 7624 Pécs, Hungary.
Róza ZákányDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
University of Debrecen · HUInstitute of Biochemistry · HUUniversity of Pecs · HU

Funding

European Union and the European Social Fund EFOP-3.6.1-16-2016-00022European Union and the European Social Fund EFOP-3.6.3-VEKOP-16-2017-00009Gedeon Richter Plc. 2020/R/20/2502National Research, Development and Innovation Fund, Hungary K131588National Research, Development and Innovation Fund of Hungary TKP2020-NKA-04National Research, Development and Innovation Office, Hungary FK-134304
6 · The paper itself

Abstract

We investigated the gene expression pattern of selected enzymes involved in DNA methylation and the effects of the DNA methylation inhibitor 5-azacytidine during in vitro and in vivo cartilage formation. Based on the data of a PCR array performed on chondrifying BMP2-overexpressing C3H10T1/2 cells, the relative expressions of

Indexed as

Epigenesis, GeneticAnimalsAzacitidineBone Morphogenetic Protein 2Cell LineCell ProliferationCell SurvivalChondrogenesisDNA-Binding ProteinsDNA MethylationDNA Methyltransferase 3AExtracellular MatrixGene Expression Regulation, DevelopmentalMiceModels, BiologicalN-AcetylglucosaminyltransferasesAzacitidineBone Morphogenetic Protein 2DNA-Binding ProteinsDNA Methyltransferase 3ADnmt3a protein, mouseN-AcetylglucosaminyltransferasesOgt protein, mouseProto-Oncogene ProteinsTET1 protein, mouse5-azacytidineC3H10T1/2cell differentiationchondrocytechondrogenesisDNA methylationmicromass culturemouse embryo

Identifiers

PMID34685658
PMCPMC8534543
OpenAlexW3204821041

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.