Evidence map›Paper›PMID 34685564›Full record

ReviewCells2021

Interplay between Gut Lymphatic Vessels and Microbiota.

Eleonora Solari, Cristiana Marcozzi, Daniela Negrini, Andrea Moriondo

Abstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. From defense to disease: the multifaceted role of lymphatics during infection.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Skin microbiome considerations for long haul space flights.Frontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eleonora SolariDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-5962-8976
Cristiana MarcozziDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.ORCID 0000-0003-2242-2880
Daniela NegriniDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.
Andrea MoriondoDepartment of Medicine and Surgery, School of Medicine, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-9423-5446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphatic vessels play a distinctive role in draining fluid, molecules and even cells from interstitial and serosal spaces back to the blood circulation. Lymph vessels of the gut, and especially those located in the villi (called lacteals), not only serve this primary function, but are also responsible for the transport of lipid moieties absorbed by the intestinal mucosa and serve as a second line of defence against possible bacterial infections. Here, we briefly review the current knowledge of the general mechanisms allowing lymph drainage and propulsion and will focus on the most recent findings on the mutual relationship between lacteals and intestinal microbiota.

Indexed as

Gastrointestinal MicrobiomeHumansLymphatic Vesselslacteallymphatic vesselmicrobiota

Identifiers

PMID34685564
PMCPMC8534149

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.