Evidence map›Paper›PMID 34685467›Full record

ArticleLife (Basel, Switzerland)2021

The Timing and Effects of Low-Dose Ethanol Treatment on Acetaminophen-Induced Liver Injury.

Fu-Chao Liu, Huang-Ping Yu, Chia-Chih Liao, An-Hsun Chou, Hung-Chen Lee

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Multimodal Analgesia in the Aesthetic Plastic Surgery: Concepts and Strategies.Plastic and reconstructive surgery. Global open · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fu-Chao LiuDepartment of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0003-1712-4053
Huang-Ping YuDepartment of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-3030-0560
Chia-Chih LiaoDepartment of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
An-Hsun ChouDepartment of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Hung-Chen LeeDepartment of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0003-2793-0630
Chang Gung University · TW

Funding

Chang Gung Memorial Hospital, Linkou CMRPG3K0911-2Chang Gung Memorial Hospital, Linkou CMRPG3K1471-2Chang Gung Memorial Hospital, Linkou CMRPG3L0611-3Ministry of Science and Technology, Taiwan MOST 110-2314-B-182A-083-MY3Ministry of Science and Technology, Taiwan MOST 110-2314-B-182A-085-MY2
6 · The paper itself

Abstract

Acetaminophen (APAP) overdose is the major cause of drug-induced liver injury and acute liver failure. Approximately 10% of APAP is metabolized by cytochrome P450 (CYP2E1) into toxic

Indexed as

acetaminophenalcoholCYP2E1cytochrome P450ethanolinflammationliver injuryneutrophil

Identifiers

PMID34685467
PMCPMC8539755
OpenAlexW3206380631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.