Evidence map›Paper›PMID 34685459›Full record

ReviewLife (Basel, Switzerland)2021

Molecular and Cellular Mechanisms of Vascular Development in Zebrafish.

Jean Eberlein, Lukas Herdt, Julian Malchow, Annegret Rittershaus, Stefan Baumeister, Christian Sm Helker

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Zebrafish in Cardiovascular Disease Research: from Model to Application.International journal of biological sciences · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jean EberleinCell Signaling and Dynamics, Faculty of Biology, Philipps-University Marburg, 35043 Marburg, Germany.
Lukas HerdtCell Signaling and Dynamics, Faculty of Biology, Philipps-University Marburg, 35043 Marburg, Germany.ORCID 0000-0002-2177-3382
Julian MalchowCell Signaling and Dynamics, Faculty of Biology, Philipps-University Marburg, 35043 Marburg, Germany.
Annegret RittershausCell Signaling and Dynamics, Faculty of Biology, Philipps-University Marburg, 35043 Marburg, Germany.
Stefan BaumeisterCell Signaling and Dynamics, Faculty of Biology, Philipps-University Marburg, 35043 Marburg, Germany.ORCID 0000-0002-7784-3474
Christian Sm HelkerCell Signaling and Dynamics, Faculty of Biology, Philipps-University Marburg, 35043 Marburg, Germany.ORCID 0000-0003-0427-5338
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The establishment of a functional cardiovascular system is crucial for the development of all vertebrates. Defects in the development of the cardiovascular system lead to cardiovascular diseases, which are among the top 10 causes of death worldwide. However, we are just beginning to understand which signaling pathways guide blood vessel growth in different tissues and organs. The advantages of the model organism zebrafish (

Indexed as

angiogenesisApelinblood vesselsendothelial cellssignaling pathwaysvasculogenesisVegfzebrafish

Identifiers

PMID34685459
PMCPMC8539546
OpenAlexW3206048295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.