Evidence map›Paper›PMID 34685436›Full record

ArticleLife (Basel, Switzerland)2021

Strain Echocardiography Is a Promising Tool for the Prognostic Assessment of Sarcoidosis.

Paolo Cameli, Maria Concetta Pastore, Giulia Elena Mandoli, Mariangela Vigna, Giuseppe De Carli, Laura Bergantini, Miriana d'Alessandro, Nicolò Ghionzoli, Elena Bargagli, Matteo Cameli

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paolo CameliRespiratory Diseases Unit, Department of Medical Sciences, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0001-8639-2882
Maria Concetta PastoreDepartment of Medical Biotechnologies, Section of Cardiology, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-7223-141X
Giulia Elena MandoliDepartment of Medical Biotechnologies, Section of Cardiology, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-3184-3006
Mariangela VignaDepartment of Medical Biotechnologies, Section of Cardiology, University of Siena, 53100 Siena, Italy.
Giuseppe De CarliDepartment of Medical Biotechnologies, Section of Cardiology, University of Siena, 53100 Siena, Italy.
Laura BergantiniRespiratory Diseases Unit, Department of Medical and Surgical Sciences & Neurosciences, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0002-1118-3223
Miriana d'AlessandroRespiratory Diseases Unit, Department of Medical and Surgical Sciences & Neurosciences, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0002-2368-5722
Nicolò GhionzoliDepartment of Medical Biotechnologies, Section of Cardiology, University of Siena, 53100 Siena, Italy.
Elena BargagliRespiratory Diseases Unit, Department of Medical and Surgical Sciences & Neurosciences, Siena University Hospital, 53100 Siena, Italy.ORCID 0000-0002-8351-3703
Matteo CameliDepartment of Medical Biotechnologies, Section of Cardiology, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3872-8964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcoidosis is a systemic chronic granulomatous disease with significant morbidity and mortality. Although basic transthoracic echocardiography (TTE) is not recommended for the assessment of sarcoidosis, speckle tracking echocardiography (STE) has emerged as more sensitive for the early detection of cardiac sarcoidosis and its outcome. The aim of the study was to assess the utility of left atrial and left ventricular longitudinal STE for the prediction of major adverse cardiac events (MACE) and sarcoidosis relapses. We enrolled 172 consecutive patients with sarcoidosis who underwent TTE and pulmonary function tests (PFTs). All patients were followed for a sarcoidosis relapse and MACE. During a median follow-up of 2217 days, 8 deaths, 23 MACE and 36 sarcoidosis relapses were observed. LV global longitudinal strain (GLS) was significantly lower in patients with MACE (

Indexed as

biomarkersechocardiographysarcoidosisstrain

Identifiers

PMID34685436
PMCPMC8541057

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.