Evidence map›Paper›PMID 34685415›Full record

ReviewLife (Basel, Switzerland)2021

Small Extracellular Vesicles: Functions and Potential Clinical Applications as Cancer Biomarkers.

Yi Wang, Ruichen Zhao, Xueqiao Jiao, Longyuan Wu, Yuxuan Wei, Fuxiu Shi, Junpei Zhong, Lixia Xiong

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Emerging Roles of Using Small Extracellular Vesicles as an Anti-Cancer Drug.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yi WangDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.ORCID 0000-0003-4848-131X
Ruichen ZhaoDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.ORCID 0000-0002-0966-9232
Xueqiao JiaoDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.ORCID 0000-0002-7193-8077
Longyuan WuDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.ORCID 0000-0002-6751-8715
Yuxuan WeiDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.
Fuxiu ShiDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.ORCID 0000-0001-8312-8808
Junpei ZhongDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.ORCID 0000-0002-7811-9816
Lixia XiongDepartment of Pathophysiology, Medical College, Nanchang University, 461 Bayi Road, Nanchang 330006, China.ORCID 0000-0003-3769-2496
Nanchang University · CN

Funding

National Natural Science Foundation of China No. 31860317, No. 32160169National natural science foundation of Jiangxi province No. 20202BAB206056the college students innovation training program of Nanchang University No. S202010403034the postgraduates innovation special fund project of Nanchang University No.YC2020-S049
6 · The paper itself

Abstract

Cancer, as the second leading cause of death worldwide, is a major public health concern that imposes a heavy social and economic burden. Effective approaches for either diagnosis or therapy of most cancers are still lacking. Dynamic monitoring and personalized therapy are the main directions for cancer research. Cancer-derived extracellular vesicles (EVs) are potential disease biomarkers. Cancer EVs, including small EVs (sEVs), contain unique biomolecules (protein, nucleic acid, and lipids) at various stages of carcinogenesis. In this review, we discuss the biogenesis of sEVs, and their functions in cancer, revealing the potential applications of sEVs as cancer biomarkers.

Indexed as

cancerclinical applicationsliquid biopsysEVs

Identifiers

PMID34685415
PMCPMC8541078
OpenAlexW3201751336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.