Evidence map›Paper›PMID 34685379›Full record

ArticleLife (Basel, Switzerland)2021

Serum Cytokine Profile, Beta-Hexosaminidase A Enzymatic Activity and GM

Alisa A Shaimardanova, Daria S Chulpanova, Valeriya V Solovyeva, Ekaterina E Garanina, Ilnur I Salafutdinov, Alexander Vladimirovich Laikov, Vadim V Kursenko, Lisa Chakrabarti, Ekaterina Yu Zakharova, Tatiana M Bukina and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Gene Therapy of Sphingolipid Metabolic Disorders.International journal of molecular sciences · 2023
    Review
  5. Article
  6. [Progressive psychomotor regression for 2.5 years in a boy aged 5 years].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Alisa A ShaimardanovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Daria S ChulpanovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0001-5546-840X
Valeriya V SolovyevaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0002-8776-3662
Ekaterina E GaraninaInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Ilnur I SalafutdinovInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Alexander Vladimirovich LaikovInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0002-4250-2645
Vadim V KursenkoIndividual Entrepreneur Kursenko V.V., 423800 Naberezhnye Chelny, Russia.
Lisa ChakrabartiSchool of Veterinary Medicine and Science, University of Nottingham, Nottingham NG7 2RD, UK.ORCID 0000-0001-7213-6837
Ekaterina Yu ZakharovaResearch Centre for Medical Genetics, 115478 Moscow, Russia.
Tatiana M BukinaResearch Centre for Medical Genetics, 115478 Moscow, Russia.
Galina V BaydakovaResearch Centre for Medical Genetics, 115478 Moscow, Russia.
Albert Anatolyevich RizvanovInstitute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0002-9427-5739
Kazan Federal University · RUResearch Centre for Medical Genetics · RUNaberezhnye Chelny State Pedagogical Institute · RUUniversity of Nottingham · GB

Funding

Ministry of Science and Higher Education of the Russian Federation #0671-2020-0058
6 · The paper itself

Abstract

Tay-Sachs disease (TSD) is a progressive neurodegenerative disorder that occurs due to a deficiency of a β hexosaminidase A (HexA) enzyme, resulting in the accumulation of GM

Indexed as

cord blood cell transplantationcurcumincytokine profileGM2 gangliosidosislysosomal storage diseasesTay-Sachs diseaseβ hexosaminidase A

Identifiers

PMID34685379
PMCPMC8539434
OpenAlexW3202096716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.