Evidence map›Paper›PMID 34685218›Full record

ArticlePolymers2021

Preparation of a Cage-Type Polyglycolic Acid/Collagen Nanofiber Blend with Improved Surface Wettability and Handling Properties for Potential Biomedical Applications.

Sofia El-Ghazali, Hisatoshi Kobayashi, Muzamil Khatri, Duy-Nam Phan, Zeeshan Khatri, Sheeraz Khan Mahar, Shunichi Kobayashi, Ick-Soo Kim

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Sofia El-GhazaliFaculty of Science and Technology, Division of Biomedical Engineering, Department of Biomedical Engineering, Shinshu University, Tokida 3-15-1, Ueda 386-8567, Nagano Prefecture, Japan.
Hisatoshi KobayashiInternational Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Tsukuba 305-0044, Ibaraki Prefecture, Japan.
Muzamil KhatriNano Fusion Technology Research Group, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Tokida 3-15-1, Ueda 386-8567, Nagano Prefecture, Japan.ORCID 0000-0003-2187-0681
Duy-Nam PhanSchool of Textile-Leather and Fashion, Hanoi University of Science and Technology, No 1 Dai Co Viet Street, Hanoi City 10000, Vietnam.ORCID 0000-0001-5171-8256
Zeeshan KhatriCenter of Excellence in Nanotechnology and Materials, Mehran University of Engineering and Technology, Jamshoro 76060, Sindh, Pakistan.ORCID 0000-0001-8779-3805
Sheeraz Khan MaharCenter of Excellence in Nanotechnology and Materials, Mehran University of Engineering and Technology, Jamshoro 76060, Sindh, Pakistan.ORCID 0000-0002-7752-5986
Shunichi KobayashiFaculty of Science and Technology, Division of Biomedical Engineering, Department of Biomedical Engineering, Shinshu University, Tokida 3-15-1, Ueda 386-8567, Nagano Prefecture, Japan.
Ick-Soo KimNano Fusion Technology Research Group, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Tokida 3-15-1, Ueda 386-8567, Nagano Prefecture, Japan.ORCID 0000-0003-2244-4369
Shinshu University · JPMehran University of Engineering and Technology · PKHanoi University of Science and Technology · VNNational Institute for Materials Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospun biobased polymeric nanofiber blends are widely used as biomaterials for different applications, such as tissue engineering and cell adhesion; however, their surface wettability and handling require further improvements for their practical utilization in the assistance of surgical operations. Therefore, Polyglycolic acid (PGA) and collagen-based nanofibers with three different ratios (40:60, 50:50 and 60:40) were prepared using the electrospinning method, and their surface wettability was improved using ozonation and plasma (nitrogen) treatment. The effect on the wettability and the morphology of pristine and blended PGA and collagen nanofibers was assessed using the WCA test and SEM, respectively. It was observed that PGA/collagen with the ratio 60:40 was the optimal blend, which resulted in nanofibers with easy handling and bead-free morphology that could maintain their structural integrity even after the surface treatments, imparting hydrophilicity on the surface, which can be advantageous for cell adhesion applications. Additionally, a cage-type collector was used during the electrospinning process to provide better handling properties to (PGA/collagen 60:40) blend. The resultant nanofiber mat was then incorporated with activated poly (α,β-malic acid) to improve its surface hydrophilicity. The chemical composition of PGA/collagen 60:40 was assessed using FTIR spectroscopy, supported by Raman spectroscopy.

Indexed as

cage-type collectorelectrospinninghandling propertiesnanofiber blendozonationplasma treatmentsurface modification

Identifiers

PMID34685218
PMCPMC8541674
OpenAlexW3206802932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.