Evidence map›Paper›PMID 34685172›Full record

ArticleNanomaterials (Basel, Switzerland)2021

About the Influence of PEG Spacers on the Cytotoxicity of Titanate Nanotubes-Docetaxel Nanohybrids against a Prostate Cancer Cell Line.

Alexis Loiseau, Julien Boudon, Céline Mirjolet, Véronique Morgand, Nadine Millot

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexis LoiseauLaboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS Université Bourgogne Franche-Comté, BP 47870, CEDEX, 21078 Dijon, France.ORCID 0000-0003-0881-5637
Julien BoudonLaboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS Université Bourgogne Franche-Comté, BP 47870, CEDEX, 21078 Dijon, France.ORCID 0000-0002-2500-5030
Céline MirjoletINSERM 1231, Cadir Team, CEDEX, 21078 Dijon, France.ORCID 0000-0003-0047-9421
Véronique MorgandRadiotherapy Department, Georges-Francois Leclerc Cancer Center, CEDEX, 21079 Dijon, France.
Nadine MillotLaboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS Université Bourgogne Franche-Comté, BP 47870, CEDEX, 21078 Dijon, France.ORCID 0000-0002-0127-3858

Funding

Cancéropôle Est Emergence 2015EIPHI Graduate School ANR-17-EURE-0002European Union PO FEDER-FSE Bourgogne 2014/2020 programs
6 · The paper itself

Abstract

The association between chemotherapeutic drugs and metal oxide nanoparticles has sparked a rapidly growing interest in cancer nanomedicine. The elaboration of new engineered docetaxel (DTX)-nanocarriers based on titanate nanotubes (TiONts) was reported. The idea was to maintain the drug inside cancer cells and avoid multidrug resistance mechanisms, which often limit drug efficacy by decreasing their intracellular concentrations in tumor cells. HS-PEG

Indexed as

colloidal stabilitycytotoxicitydocetaxelpolyethylene glycolprostate cancer cellstitanate nanotubes

Identifiers

PMID34685172
PMCPMC8539671

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.